Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,230 questions · 1,303 findings · 326 reviews · Headline outcomes only

No studies found 73 · 5.6%GRADE not reported 21 · 1.6%Very low 497 · 38.1%Low 403 · 30.9%Moderate 245 · 18.8%High 64 · 4.9%

Intervention not reported

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Intervention not reported

Grief in the relatives ICG (0 to 95; > 25 = presence of complicated grief) measured at 12 months TRIG (21 to 105; lower scores indicate higher levels of grief) measured at 3 and 9 months · relatives, patients, and healthcare professionals during resucitation
1 finding from 1 review

Digital technology (web‐based platform CFHealthHub) vs usual care

Treatment burden · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) probably leads to higher treatment burden: CFQ‐R treatment burden domain score (higher score… compared with usual care (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life (QoL) We reported this outcome narratively in this review. Here, long‐term results (i.e., at the end of treatment) are presented. In the comparison PAZ versus SUN, QoL was measured using FACIT‐F (score range 0‐52; higher scores rep... · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy

The review found no eligible studies for this question.

1 finding from 1 review

CBT vs TAU

Functional disability (Higher scores indicate higher levels of disability) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs TAU

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs TAU

Pain intensity (number of people with ≥ 30% improvement) (Higher scores indicate improvement) · chronic pain (excluding headache) in adults

CBT probably leads to higher pain intensity (number of people with ≥ 30% improvement) (Higher… compared with TAU (post‐treatment) (moderate certainty).

1 finding from 1 review