Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

473 questions · 480 findings · 60 reviews · Headline outcomes only

No studies found 100 · 20.8%GRADE not reported 3 · 0.6%Very low 104 · 21.7%Low 129 · 26.9%Moderate 106 · 22.1%High 38 · 7.9%

Intervention not reported

Analgesia duration 1 mg morphine vs 4 mg/5 mg morphinetime duration from the end of surgery to the first time of analgesic consumption · patients undergoing knee arthroscopy
1 finding from 1 review

Intervention not reported

Adverse events 1 mg morphine vs 4 mg/5 mg morphinePercentage of participants with any adverse event · patients undergoing knee arthroscopy

The review found no eligible studies for this question.

1 finding from 1 review

Fingolimod 0.5 mg vs interferon beta‐1a

Participants free from MRI gadolinium‐enhancing lesions · patients with relapsing‐remitting multiple sclerosis

Fingolimod 0.5 mg probably leads to higher participants free from MRI gadolinium‐enhancing lesions compared with interferon beta‐1a (moderate certainty).

1 finding from 1 review

Fingolimod 0.5 mg vs placebo

Proportion of participants with relapse‐free survival at ≥ 12 months · patients with relapsing‐remitting multiple sclerosis

Fingolimod 0.5 mg probably leads to higher participants free from relapse compared with placebo (moderate certainty).

1 finding from 1 review

Fingolimod 0.5 mg vs placebo

Participants free from disability worsening · patients with relapsing‐remitting multiple sclerosis

Fingolimod 0.5 mg may leads to higher participants free from disability worsening compared with placebo (low certainty).

1 finding from 1 review

Fingolimod 0.5 mg vs placebo

Withdrawals due to adverse events · patients with relapsing‐remitting multiple sclerosis

It is very uncertain whether fingolimod 0.5 mg changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Fingolimod 0.5 mg vs placebo

Participants free from MRI gadolinium‐enhancing lesions · patients with relapsing‐remitting multiple sclerosis

Fingolimod 0.5 mg may leads to higher participants free from MRI gadolinium‐enhancing lesions compared with placebo (low certainty).

1 finding from 1 review