Relative DOR by reference standard (LFpen, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions
No significant reference-standard difference for LFpen at the advanced threshold (RDOR 0.96, 0.12 to 7.77).
1 finding from 1 review
Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Permanent teeth, occlusal surfaces, with suspected caries lesions
Fluorescence camera on occlusal surfaces of permanent teeth (initial-lesion threshold): accuracy similar among the three methods (very low inconsistency); heterogeneity I2=0%. Diagnostic accuracy was not formally graded (GRADE not used).
2 findings from 1 review
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 6); accuracy similar among the three methods (very low inconsistency). Heterogeneity I2=0%. Numeric pooled values not…
Studies not reported
GRADE not reported
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity. 2013 All outcomesMore advanced (dentine/cavitated) caries lesions threshold · Laboratory (in vitro) and clinical (in vivo)
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 6); pooled DOR for FC among the higher values, exceeding LFpen. Heterogeneity I2=17%. Numeric pooled values not…
Studies not reported
GRADE not reported
Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Primary teeth, occlusal surfaces, with suspected caries lesions
Laser fluorescence on occlusal surfaces of primary teeth (more advanced-lesion threshold): pooled DOR lowest for LF among the three methods; heterogeneity I2=23%. Diagnostic accuracy was not formally graded (GRADE not used).
2 findings from 1 review
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity. 2013 All outcomesMore advanced (dentine/cavitated) caries lesions threshold · Laboratory (in vitro) and clinical (in vivo)
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 7); pooled DOR lowest for LF among the three methods. Heterogeneity I2=23%. Numeric pooled values not available in the…
Studies not reported
GRADE not reported
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 7); accuracy similar among LF, LFpen and FC. Heterogeneity I2=75%. Numeric pooled values not available in the provided…
Studies not reported
GRADE not reported
Initial caries lesion detection · Primary teeth with occlusal surfaces
Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=75%; no GRADE rating was reported.
2 findings from 1 review
Specificity 0.838 [0.810, 0.864]
14 studies
GRADE not reported
Sensitivity 0.622 [0.592, 0.651]
14 studies
GRADE not reported
Intervention not reported
Risk of caries occurrence
1 finding from 1 review
School-based oral health promotion services · Alaska children
The PDHA program was projected to raise school-based oral health promotion service receipt from 53% to more than 90%, without a GRADE rating.
1 finding from 1 review
Significant caries index · Alaska children
The PDHA program was projected to reduce the SiC index 50% from 12.3 to 6.1 for children, without a GRADE rating.
1 finding from 1 review
Amalgam preparation deficiency · Alaska dental health aide therapists
Two of 13 DHAT amalgam preparations were deficient, without a GRADE rating.
1 finding from 1 review
Diagnostic accuracy (sensitivity, specificity) - not pooled · Permanent teeth (occlusal and smooth surfaces), with suspected caries lesions
Only 3 QLF studies were included, so no pooled estimate of QLF diagnostic accuracy could be calculated (evidence not graded).
1 finding from 1 review
Significant caries index · Alaska children aged 12 years
The PDHA program was projected to reduce the SiC index 70% from 10.5 to 3.3 for 12-year-olds, without a GRADE rating.
1 finding from 1 review
Infant dental caries · Pregnant Alaska Native women and their infants
No infant caries outcomes were assessed because the proposed randomized trial was discontinued.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)
A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).
1 finding from 1 review
Diagnostic accuracy (sensitivity, specificity) - not pooled · Permanent and primary teeth, smooth surfaces, with suspected caries lesions
Only 2 LF studies assessed smooth surfaces, so no pooled estimate was possible; both reported higher specificity than sensitivity (evidence not graded).
1 finding from 1 review
Retention of sealant (complete or partial retention) · Pits and fissures of permanent (posterior) teeth
High-viscosity glass-ionomer ART sealants showed 4-year retention of 68% (95% CI 61-75%); evidence ungraded.
6 findings from 1 review
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Caries-free sealed pits and fissures · Permanent teeth with sealed pits and fissures
The pooled caries-free rate was 85% at 6 years.
6 findings from 1 review
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Restoration survival · Permanent posterior teeth with single-surface cavities
The pooled survival rate was 93% at 2 years.
6 findings from 1 review
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Restoration survival · Permanent posterior teeth with multiple-surface cavities
The pooled survival rate was 41% at 2 years.
3 findings from 1 review
Survival percentage 41 [18, 67]
1 study
GRADE not reported
Survival percentage 86 [59, 98]
3 studies
GRADE not reported
Survival percentage 77 [56, 92]
1 study
GRADE not reported
Restoration survival · Primary posterior teeth with multiple-surface cavities
Multiple-surface high-viscosity glass-ionomer ART restorations in primary teeth had moderate 2-year survival (62%, 95% CI 51-73%); evidence ungraded.
3 findings from 1 review
Restoration survival · Primary posterior teeth with single-surface cavities
The pooled survival rate was 95% at 1 year.
3 findings from 1 review
Caries-free sealed pits and fissures · Pits and fissures of permanent (posterior) teeth
Pits and fissures sealed with high-viscosity glass-ionomer ART sealants remained dentine lesion-free in 100% (95% CI 99-100%) at 1-year; evidence ungraded.
6 findings from 1 review
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