Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm or low birth weight infants with PDA
Paracetamol plus ibuprofen (oral or IV) showed no clear difference in necrotizing enterocolitis during initial hospital stay (radiological… compared with ibuprofen plus placebo (oral or IV) or no intervention (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm or low birth weight infants with PDA
Paracetamol showed no clear difference in all‐cause mortality during initial hospital stay(by clinical… compared with ibuprofen (moderate certainty).
1 finding from 1 review
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm or low birth weight infants with PDA
Paracetamol showed no clear difference in necrotizing enterocolitisduring initial hospital stay (by… compared with ibuprofen (moderate certainty).
1 finding from 1 review
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm infants with PDA
Paracetamol showed no clear difference in failure of PDA closure after first course of treatment (assessed by… compared with indomethacin (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants with PDA
Paracetamol showed no clear difference in all‐cause mortality during initial hospital stay (by clinical… compared with indomethacin (low certainty).
1 finding from 1 review
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm infants with PDA
Paracetamol may leads to lower necrotizing enterocolitis during initial hospital stay (by… compared with indomethacin (low certainty).
1 finding from 1 review
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm infants with PDA
Prophylactic administration of paracetamol may leads to lower failure of PDA closure after first course (assessed by… compared with placebo or no intervention (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants with PDA
Prophylactic administration of paracetamol showed no clear difference in all‐cause mortality during initial hospital stay (by clinical… compared with placebo or no intervention (low certainty).
1 finding from 1 review
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm infants with PDA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Regression of PSR: change in number and size (in clock hours or in degrees of retinal circumference) of new blood vessels · children and adults with SCD and PSR
1 finding from 1 review
Development of new PSR: proliferation of blood vessels at a new area/progression of existing PSR after treatment · children and adults with SCD and PSR
1 finding from 1 review
Quality of life · children and adults with SCD and PSR
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · children and adults with SCD and PSR
1 finding from 1 review
Occurence of vitreous haemorrhage · children and adults with SCD and PSR
1 finding from 1 review
Adverse effects · children and adults with SCD and PSR
1 finding from 1 review
Spasticity: number of participants reporting reduction of 30% in the spasticity NRS ( · health problem or population
Summary of findings table ‐ Cannabis probably leads to higher spasticity: number of participants reporting reduction of 30% in the… compared with placebo (moderate certainty).
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · health problem or population
It is very uncertain whether summary of findings table ‐ Cannabis changes pain:number of participants reporting pain relief of 50% or greater… compared with placebo (very low certainty).
1 finding from 1 review
Patient Global Impression of Change much or very much improved · health problem or population
Summary of findings table ‐ Cannabis probably leads to higher PGIC:number of participants reporting much or very much improvement… compared with placebo (moderate certainty).
1 finding from 1 review
Health‐related quality of life. Mean change from baseline · health problem or population
1 finding from 1 review
Number withdrawn due to adverse events · health problem or population
Summary of findings table ‐ Cannabis may leads to higher withdrawn due to adverse events ( compared with placebo (low certainty).
1 finding from 1 review