Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Digital targeted client communication via mobile devices vs standard skin care or no skin care intervention

Health behaviour change ‐ Oral contraception use · Adolescents and youth age 14 to 24 years

Digital targeted client communication via mobile devices may leads to higher health behaviour change ‐ Oral contraception use compared with standard care or no intervention (low certainty).

1 finding from 1 review

Digital targeted client communication via mobile devices vs standard skin care or no skin care intervention

Health service utilization ‐ Clinic attendance for STI/HIV testing · Adolescents and youth age 14 to 24 years

It is very uncertain whether digital targeted client communication via mobile devices changes health service utilization ‐ Clinic attendance for STI/HIV testing compared with standard care or no intervention (very low certainty).

1 finding from 1 review

Digital targeted client communication via mobile devices vs standard skin care or no skin care intervention

SRH knowledge · Adolescents and youth age 14 to 24 years

Digital targeted client communication via mobile devices may leads to higher SRH knowledge compared with standard care or no intervention (low certainty).

1 finding from 1 review

Resilience interventions vs controls

Resilience Measured by: investigators measured resilience using different instruments; higher scores mean higher resilience Timing of outcome assessment: post‐intervention · healthcare students, including students in training for health professions delivering direct medical care (e.g. medical students, nursing…
1 finding from 1 review

Resilience interventions vs controls

Mental health and well‐being: depressionMeasured by: investigators measured depression using different instruments; lower scores mean lower depression Timing of outcome assessment: post‐intervention · healthcare students, including students in training for health professions delivering direct medical care (e.g. medical students, nursing…
1 finding from 1 review

Intervention not reported

Mortality at longest · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…

It is very uncertain whether the intervention changes mortality at longest (very low certainty).

1 finding from 1 review

Intervention not reported

Requirement for renal replacement therapy ( · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…

It is very uncertain whether the intervention changes requirement for renal replacement therapy ( (very low certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: prevalence of moderate to extensive caries (ICDAS 3-6) compared with clinical examination with 6-month recall (moderate certainty).

1 finding from 1 review

Resin-based fissure sealant (visible-light-polymerized) vs Fluoride varnish

Incidence of dentinal carious lesion on treated occlusal surfaces of molars or premolars (yes/no) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant (visible-light-polymerized) changes incidence of dentinal carious lesion on treated occlusal surfaces of… compared with fluoride varnish (very low certainty).

2 findings from 1 review

Fluoride varnish vs Fissure sealant (resin-based or glass ionomer)

Increment of occlusal DMFS (decayed, missing, filled surfaces) of FPMs · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel…

Fluoride varnish and fissure sealant did not differ significantly in occlusal DMFS increment of FPMs (MD 0.13, 95% CI -0.09 to 0.34; 3 RCTs; ungraded).

2 findings from 1 review