Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Probiotics vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review

LHWs to promote immunisation uptake in children vs usual care

Immunisation schedule up to date Interviews with mothers, record reviews · patients with improving immunisation uptake among children < 2 years whose vaccination is not up to date

LHWs to promote immunisation uptake in children probably leads to higher immunisation schedule up to date Interviews with mothers, record… compared with usual care (moderate certainty).

1 finding from 1 review

LHWs vs usual care

Morbidity e.g. fever, diarrhoea, ARI Verbal reports obtained during home visits, record reviews · patients with reducing mortality and morbidity in children <5 years

LHWs may leads to lower morbidity e.g. fever, diarrhoea, ARI Verbal reports obtained during… compared with usual care (low certainty).

1 finding from 1 review

LHWs vs usual care

Morbidity ‐ care seeking practice hospital record review · patients with reducing mortality and morbidity in children <5 years

LHWs showed no clear difference in morbidity ‐ care seeking practice hospital record review compared with usual care (low certainty).

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Visual acuity · 5‐ to 8‐year‐old children with amblyopia
2 findings from 1 review