Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings 1: blue‐light filtering lenses vs non blue‐light filtering IOL

Proportion of participants with adverse events with a probable causal link with the study interventions at six months · adults

Summary of findings 1: blue‐light filtering lenses may leads to lower proportion of participants with adverse events with a probable… compared with non‐blue‐light filtering lenses (low certainty).

1 finding from 1 review

Exercise vs usual care with or without sham interventions

Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised medical patients

It is very uncertain whether summary of findings table ‐ Exercise interventions changes functional ability: new incidence of delirium during hospitalisation compared with usual care with or without sham interventions (very low certainty).

1 finding from 1 review

Exercise vs usual care with or without sham interventions

Medical deterioration during hospitalisation · acutely hospitalised medical patients

It is very uncertain whether summary of findings table ‐ Exercise interventions changes medical deterioration during hospitalisation compared with usual care with or without sham interventions (very low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs medical treatment

Death or severe disability (mRS > 4) at 6 to 12 months · malignant cerebral oedema after ischaemic stroke

Summary of findings table ‐ surgical decompression leads to lower death or severe disability (mRS > 4) at 6 to 12 months compared with medical treatment alone (high certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs medical treatment

Death or moderate disability (mRS > 3) at 6 to 12 months · malignant cerebral oedema after ischaemic stroke

Summary of findings table ‐ surgical decompression probably leads to lower death or moderate disability (mRS > 3) at 6 to 12 months compared with medical treatment alone (moderate certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR DECOMPRESSION vs medical treatment

Severe disability (mRS = 5) at 6 to 12 months · malignant cerebral oedema after ischaemic stroke

Summary of findings table ‐ surgical decompression showed no clear difference in severe disability (mRS = 5) at 6 to 12 months compared with medical treatment alone (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs OnabotulinumtoxinA 20U

Participant assessment of success by analysing scores and scales ‐ 4 weeks · glabellar lines

Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in participant assessment success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).

1 finding from 1 review

Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs OnabotulinumtoxinA 20U

Major adverse events (eyelid ptosis, eyelid sensory disorder, strabismus) · glabellar lines

Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in major adverse events ‐ Any major adverse events (eyelid ptosis,… compared with onabotulinumtoxinA 20U (moderate certainty).

1 finding from 1 review

Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs OnabotulinumtoxinA 20U

Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines

Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in physician assessment of success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).

1 finding from 1 review