Cochrane · systematic review · CD014989
Surgical decompression for malignant cerebral oedema after ischaemic stroke
Dower, A, Mulcahy, M, Maharaj, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 42.9%Very low 0 · 0%Low 1 · 14.3%Moderate 1 · 14.3%High 2 · 28.6%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ surgical decompression vs. medical treatment alone for malignant cerebral oedema after ischaemic stroke
Population: malignant cerebral oedema after ischaemic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death at 6 to 12 months Summary of findings table ‐ surgical decompression vs medical treatment alone | OR 0.18 [0.12, 0.27] | 9 studies · 513 participants | High |
Death or severe disability (mRS > 4) at 6 to 12 months Summary of findings table ‐ surgical decompression vs medical treatment alone | OR 0.22 [0.15, 0.32] | 9 studies · 513 participants | High |
Death or moderate disability (mRS > 3) at 6 to 12 months Summary of findings table ‐ surgical decompression vs medical treatment alone | OR 0.34 [0.22, 0.52] | 9 studies · 513 participants | Moderate Downgraded: inconsistency |
Severe disability (mRS = 5) at 6 to 12 months Summary of findings table ‐ surgical decompression vs medical treatment alone | OR 0.73 [0.36, 1.44] | 9 studies · 262 participants | Low Downgraded: inconsistency |
Adverse events Summary of findings table ‐ surgical decompression vs medical treatment alone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Hydrocephalus Summary of findings table ‐ surgical decompression vs medical treatment alone | no estimate extracted | 0 studies · 0 participants | Ungraded |
Reoperation Summary of findings table ‐ surgical decompression vs medical treatment alone | no estimate extracted | 0 studies · 0 participants | Ungraded |