Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,234 questions · 3,357 findings · 396 reviews

No studies found 803 · 23.9%GRADE not reported 270 · 8%Very low 757 · 22.5%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Intervention not reported

Progression of DRa · people with type 2 diabetes

The intervention showed no clear difference in progression of DRa (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of a reduction in visual acuity of 10 ETDR letters or more · people with type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Incidence of PDR · people with type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Incidence of DMOa · people with type 2 diabetes

The intervention showed no clear difference in incidence of DMOa (moderate certainty).

1 finding from 1 review

Intervention not reported

Mean vision‐related quality of life · people with type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

SAEa · people with type 2 diabetes

The intervention leads to higher SAEa (high certainty).

1 finding from 1 review

Immune checkpoint inhibitors vs any first‐line chemotherapy

Time to death from any cause Range of · participants with advanced or metastatic muscle invasive bladder cancer

Immune checkpoint inhibitors showed no clear difference in time to death from any cause Range of compared with any first‐line chemotherapy (moderate certainty).

1 finding from 1 review

Immune checkpoint inhibitors vs any second‐line chemotherapy

Time to progression · participants with advanced or metastatic muscle invasive bladder cancer

It is very uncertain whether immune checkpoint inhibitors changes time to disease progression Range of compared with any second‐line chemotherapy (very low certainty).

1 finding from 1 review

Immune checkpoint inhibitors vs any second‐line chemotherapy

Discontinuation of medication due to adverse events · participants with advanced or metastatic muscle invasive bladder cancer

Immune checkpoint inhibitors may leads to lower discontinuation due to adverse events Range of compared with any second‐line chemotherapy (low certainty).

1 finding from 1 review

Immune checkpoint inhibitors vs any first‐line chemotherapy

Adverse events grade 3 to 5 Range of · participants with advanced or metastatic muscle invasive bladder cancer

Immune checkpoint inhibitors probably leads to lower adverse events grade 3 to 5 Range of compared with any first‐line chemotherapy (moderate certainty).

1 finding from 1 review