Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Fixed reduction of dialysate temperature vs standard dialysate temperature

Discomfort rate · patients requiring haemodialysis

It is very uncertain whether fixed reduction of dialysate temperature changes discomfort rate compared with standard dialysate temperature (very low certainty).

1 finding from 1 review

Intervention not reported

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Protocol‐directed sedation management vs usual care

ICU mortality · mechanically ventilated ICU adults and children requiring sedation management

Protocol‐directed sedation management showed no clear difference in ICU mortality compared with usual care (low certainty).

1 finding from 1 review