Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,234 questions · 3,357 findings · 396 reviews

No studies found 803 · 23.9%GRADE not reported 270 · 8%Very low 757 · 22.5%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics

It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).

1 finding from 1 review

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Adverse events: hypotension · type 1 or type 2 diabetics

Blood pressure intervention/intensive blood pressure intervention may leads to higher adverse events—hypotension compared with placebo/standard blood pressure intervention (low certainty).

1 finding from 1 review

Intervention not reported

Gestational diabetes mellitus · pregnant women (women with pre‐existing type 1 or type 2 diabetes are NOT included)

It is very uncertain whether the intervention changes gestational diabetes mellitus (very low certainty).

1 finding from 1 review