Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

Intervention not reported

Catheter‐related thrombosis at any time during catheter stay · Children with central venous catheter

The intervention showed no clear difference in catheter‐related thrombosis at any time during catheter stay (moderate certainty).

1 finding from 1 review

Intervention not reported

Catheter‐related blood stream infection and CVC‐related colonization · Children with central venous catheter

The intervention may leads to lower catheter‐related blood stream infection and CVC‐related colonization (low certainty).

1 finding from 1 review

Intervention not reported

SGRQ Scores range from 0 to 100, with higher scores indicating more limitations · 18 to 80 years of age with bronchiectasis

The intervention showed no clear difference in SGRQ Scores range from 0 to 100, with higher scores indicating more… (low certainty).

1 finding from 1 review

Intervention not reported

TDI Total scores range from ‐ 9 to +9. The lower the score, the greater the deterioration in severity of dyspnoea, MCID ≥ 1 · 18 to 80 years of age with bronchiectasis

The intervention may leads to higher TDI Total scores range from ‐ 9 to +9. The lower the score, the… (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Number of participants with worsening scores in corporal atrophy · people with pre‐malignant lesions

Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal atrophy compared with control (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Number of participants with worsening scores in corporal intestinal metaplasia · people with pre‐malignant lesions

Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal intestinal… compared with control (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Increase in the number of participants with simple (diffuse) hyperplasia after treatment · people with pre‐malignant lesions

It is very uncertain whether proton pump inhibitor changes increase in the number of participants with simple (diffuse)… compared with control (very low certainty).

1 finding from 1 review