Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Silicone gel sheeting vs silicone gel
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
Pain · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs silicone gel
CI: Confidence interval · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Scar severity assessed by health professionals with VSS score from 0 to 14 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 20 participantsLow
Silicone gel sheeting vs topical onion extract
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Pain · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs topical onion extract
CI: Confidence interval · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Scar severity assessed by health professionals with scar index score from 0 to 14 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 55 participantsVery low
Silicone gel sheeting vs polyurethane
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Pain · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs polyurethane
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Pain assessed by VAS score from 0 to 10 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 34 participantsLow
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Scar severity assessed by health professionals · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Pain assessed by modified VSS (unclear scale) · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 38 participantsVery low
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs self‐adhesive propylene glycol and hydroxyethyl cellulose sheeting
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Scar severity assessed by health professionals · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Scar severity validated by participants · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Adverse events · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Pain assessed by a Patient and Observer Scar Assessment Scale from 0 to 10 · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extracted1 study · 55 participantsVery low
Silicone gel sheeting vs Gecko Nanoplast
Adherence to treatment · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs Gecko Nanoplast
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Health‐related quality of life · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
Cost effectiveness · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs no silicone gel sheeting
CI: Confidence interval · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Silicone gel sheeting vs pressure garments
Scar severity assessed by health professionals · people with hypertrophic scars
Silicone gel sheeting for treating hypertrophic scars (2021) · Cochrane
no estimate extractedNRNo studies
Compression bandages or stockings vs no compression
Time‐to‐complete wound healing · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted5 studies · 733 participantsModerate
Compression bandages or stockings vs no compression
Proportion of wounds completely healed during · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted10 studies · 1215 participantsModerate
Compression bandages or stockings vs no compression
Adverse events · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted3 studies · 585 participantsVery low
Compression bandages or stockings vs no compression
Participant health‐related quality of life/health status · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted4 studies · 859 participantsLow
Compression bandages or stockings vs no compression
Cost effectiveness · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted3 studies · 486 participantsVery low
Compression bandages or stockings vs no compression
Mean pain scoremedian · people with venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers (2021) · Cochrane
no estimate extracted5 studies · 859 participantsModerate
Alternating pressure (active) air surfaces vs foam surfaces
Proportion of participants developing a new pressure ulcer · pressure ulcer prevention
Alternating pressure (active) air surfaces for preventing pressure ulcers (2021) · Cochrane
RR 0.63 [0.34, 1.17]4 studies · 2247 participantsLow