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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,206 questions in 117 reviews · Common Mental Disorders
current versionsNo studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR escitalopram:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Low |
Intervention NR escitalopram:sertraline · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Low |
Intervention NR escitalopram:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Moderate |
Intervention NR mirtazapine:citalopram · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR escitalopram:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR escitalopram:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR mirtazapine:fluoxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR fluoxetine:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Low |
Intervention NR fluoxetine:sertraline · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Low |
Intervention NR fluoxetine:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR mirtazapine:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR mirtazapine:sertraline · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR mirtazapine:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Intervention NR mirtazapine:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane | no estimate extracted | NR | Very low |
Mindfulness vs no treatment or waiting list  Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | NR | No studies |
Mindfulness vs no treatment or waiting list Suicidal ideation Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | NR | No studies |
Mindfulness vs no treatment or waiting list Suicidal behaviour Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | NR | No studies |
Mindfulness vs no treatment or waiting list Anxiety Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 4 studies · 255 participants | Very low |
Mindfulness vs no treatment or waiting list Depression Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 4 studies · 250 participants | Low |
Mindfulness vs no treatment or waiting list Stress (immediately post‐intervention) Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 8 studies · 474 participants | Low |
Mindfulness vs no treatment or waiting list Stress (later time points) Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 4 studies · 233 participants | Low |
Mindfulness vs no treatment or waiting list Burnout Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 3 studies · 91 participants | Very low |
Mindfulness vs no treatment or waiting list Academic performance Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 2 studies · 79 participants | Very low |
Mindfulness vs no treatment or waiting list Quality of life Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | 1 study · 167 participants | Low |
Mindfulness vs no treatment or waiting list Deliberate self‐harm Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior… (2021) · Cochrane | no estimate extracted | NR | No studies |
Paradoxical intention therapy vs diazepam Reduction in physical signs (number of patients without any conversive attacks in last 2 weeks) End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | RR 1.44 [0.91, 2.28] | 1 study · 30 participants | Very low |
Hypnosis vs wait list Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Hypnosis vs wait list Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Hypnosis vs wait list Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Behavioural therapy plus treatment as usual vs treatment Reduction in physical signs Number of weekly seizures, as assessed by daily self‐reported treatment diary End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 18 participants | Very low |
Behavioural therapy plus treatment as usual vs treatment Reduction in physical signs (symptom severity) Measured by Clinical Global Impression scale (lower is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 90 participants | Very low |
Behavioural therapy plus treatment as usual vs treatment Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Behavioural therapy plus treatment as usual vs treatment Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Behavioural therapy plus treatment as usual vs treatment Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Cognitive behavioural therapy as vs standard medical care Reduction in physical signs Reduction in monthly seizure frequency as assessed by a daily self‐reported seizure diary End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | RR 1.56 [0.39, 6.19] | 1 study · 16 participants | Very low |
Cognitive behavioural therapy as vs standard medical care Reduction in physical signs Monthly seizure frequency as assessed by a daily self‐reported seizure diary (lower is better) End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 61 participants | Low |
Paradoxical intention therapy vs diazepam Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Cognitive behavioural therapy as vs standard medical care Reduction in physical sign Seizure freedom as assessed by a daily self‐reported seizure diary End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | RR 2.33 [0.3, 17.88] | 1 study · 16 participants | Very low |
Cognitive behavioural therapy as vs standard medical care Level of functioning As measured by the GAF (range 0–100) scale and the WSAS scale (0–40) (lower is better) End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 2 studies · 74 participants | Very low |
Cognitive behavioural therapy as vs standard medical care Quality of life As assessed by QOLIE31 (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 16 participants | Very low |
Cognitive behavioural therapy as vs standard medical care Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Psychoeducational follow‐up programme vs treatment Reduction in physical signs End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Psychoeducational follow‐up programme vs treatment Level of functioning As assessed by WSAS scale (lower is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 43 participants | Very low |
Psychoeducational follow‐up programme vs treatment Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Psychoeducational follow‐up programme vs treatment Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Specialised cognitive behavioural therapy‐based physiotherapy vs waitlist Reduction in physical signs End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Specialised cognitive behavioural therapy‐based physiotherapy vs waitlist Level of functioning As measured by FIM (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | 1 study · 118 participants | Low |
Paradoxical intention therapy vs diazepam Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Specialised cognitive behavioural therapy‐based physiotherapy vs waitlist Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Specialised cognitive behavioural therapy‐based physiotherapy vs waitlist Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria Psychosocial interventions for conversion and dissociative disorders in adults (2020) · Cochrane | no estimate extracted | NR | No studies |