Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

370 questions · 394 findings · 64 reviews

No studies found 88 · 22.3%GRADE not reported 20 · 5.1%Very low 74 · 18.8%Low 115 · 29.2%Moderate 87 · 22.1%High 10 · 2.5%

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Mean blood loss (mL) (trialist defined) · women with primary atonic postpartum haemorrhage following vaginal delivery

The review found no eligible studies for this question.

1 finding from 1 review

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Blood transfusion (red cell or whole blood) · women with primary atonic postpartum haemorrhage following vaginal delivery

It is very uncertain whether bakri balloon tamponade changes blood transfusion (red cell or whole blood) compared with condom‐loaded Foley Catheter (one intrauterine tamponade compared to… (very low certainty).

1 finding from 1 review

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Side effects of the intervention (e.g. trauma, necrosis) · women with primary atonic postpartum haemorrhage following vaginal delivery

The review found no eligible studies for this question.

1 finding from 1 review

External uterine compression (all methods) plus normal care vs normal care

Blood transfusion (red cell or whole blood) · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

It is very uncertain whether external uterine compression (all methods) plus normal care changes blood transfusion (red cell or whole blood) compared with normal care (very low certainty).

1 finding from 1 review

External uterine compression (all methods) plus normal care vs normal care

Side effects of the intervention (e.g. trauma, necrosis) ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

Higher‐dose vs lower‐dose nicotine patch

Smoking cessation · people who smoke

Higher‐dose showed no clear difference in smoking cessation ‐ 42/44 mg versus 21/22 mg (24‐hour patches) compared with lower‐dose nicotine patch (moderate certainty).

3 findings from 1 review

Higher‐dose vs lower‐dose nicotine patch

SAEs · people who smoke

Higher‐dose showed no clear difference in overall SAEs ‐ 42/44 mg versus 21/22 mg (24 hr patches) compared with lower‐dose nicotine patch (low certainty).

2 findings from 1 review

Higher‐dose vs lower‐dose nicotine patch

Treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) · people who smoke

Higher‐dose showed no clear difference in treatment withdrawals ‐ 21 mg versus 14 mg (24‐hour patches) compared with lower‐dose nicotine patch (low certainty).

1 finding from 1 review