Findings

What do systematic reviews say?

502 questions · 522 findings · 57 reviews

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No studies found 184 · 35.2%GRADE not reported 153 · 29.3%Very low 86 · 16.5%Low 51 · 9.8%Moderate 38 · 7.3%High 10 · 1.9%

Intervention not reported

Maximum voluntary contraction in mitochondrial diseases % · patients with metabolic myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 38 participants
High

Intervention not reported

Maximum voluntary contraction in glycogen storage disease type V % · patients with metabolic myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
High

Intervention not reported

Upper extremity maximum voluntary isometric contraction score at 3 months Quantitative Muscle Assessment (QMA) system. Data were normalized, summed and averaged to yield an U/E megascore (higher is better). · people with amyotrophic lateral sclerosis or motor neuron disease

1 finding from 1 review

Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Moderate

Intervention not reported

Lower extremity maximum voluntary isometric contraction score at 3 months Quantitative Muscle Assessment (QMA) system. Data were normalized, summed and averaged to yield a L/E megascore (higher is better). · people with amyotrophic lateral sclerosis or motor neuron disease

1 finding from 1 review

Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Moderate

Fluoride varnish vs placebo or no treatment

Caries increment on primary (deciduous) tooth surfaces (d(e/m)fs), prevented fraction · Children and adolescents aged 16 years or less

1 finding from 1 review

Fluoride varnishes for preventing dental caries in children and adolescents 2013 · Cochrane All outcomes
At least 1 year · Primary/deciduous dentition
PF 0.37 [0.24, 0.51]
10 studies · 3804 participants
Moderate

Strengthening exercise vs no exercise

Change in maximal isometric voluntary contraction force (Nm) · patients with people with peripheral neuropathy

1 finding from 1 review

Exercise for people with peripheral neuropathy 2004 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Moderate

ARP with xenograft (bone graft) vs Extraction alone

Marginal bone level change · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
7 months
Peri-implant marginal bone level changes obtained after 7 months (Barone 2012); no statistically significant differences between the two groups (Analysis 1.5)
1 study
GRADE not reported

ARP with xenograft (bone graft) vs Extraction alone

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
MD -1.18 [-1.82, -0.54]
6 studies · 184 participants
Very low

ARP with alloplast vs Extraction alone

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

ARP with xenograft (bone graft) vs Extraction alone

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
Outcome not reported
0 studies
No studies found

ARP with xenograft (bone graft) vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
MD -1.35 [-2.0, -0.7]
6 studies · 184 participants
Very low

ARP with alloplast vs Extraction alone

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

ARP with xenograft (bone graft) vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
1 trial (Cha 2019) reported delayed healing with partial exposure of the buccal plate at suture removal by 1 participant in the test group; another trial (Festa 2013) reported pain and swelling
2 studies · 54 participants
Low

ARP with xenograft (bone graft) vs Extraction alone

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes implant failure rate compared with extraction alone (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
RR 1.0 [0.07, 14.9]
2 studies · 70 participants
Very low

ARP with alloplast vs Extraction alone

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

ARP with alloplast vs Extraction alone

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Outcome not reported
0 studies
No studies found

ARP with alloplast vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
MD -3.73 [-4.05, -3.41]
1 study · 15 participants
Very low

ARP with alloplast vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 months
Included study (Madan 2014) reported there were no adverse effects
1 study · 15 participants
Very low

ARP with xenograft (bone graft) vs Extraction alone

It is very uncertain whether ARP with xenograft (bone graft) changes need for additional augmentation prior to implant placement compared with extraction alone (very low certainty).

1 finding from 1 review

Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development 2021 · Cochrane All outcomes
6 to 36 months
RR 0.68 [0.29, 1.62]
4 studies · 154 participants
Very low

Trifocal intraocular lenses vs bifocal intraocular lenses after cataract extraction among participants with presbyopia

Visual acuity · participants (> 30 years) with cataract and presbyopia

1 finding from 1 review

Trifocal intraocular lenses versus bifocal intraocular lenses after cataract extraction among participants with… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 107 participants
Low