What do systematic reviews say?

Aldosterone antagonists vs placebo or usual care

Aldosterone antagonists probably leads to higher AKI compared with placebo or standard care (moderate certainty).

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  RR 2.04 [1.05, 3.97]
  5 studies · 1446 participants
  Moderate

Aldosterone antagonists vs placebo or usual care

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 1193 participants
  Very low

Aldosterone antagonists vs placebo or usual care

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 1144 participants
  Low

Aldosterone antagonists vs diuretics

The review found no eligible studies for this question.

• Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Isothermal dialysate vs thermoneutral dialysate

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Isothermal dialysate vs thermoneutral dialysate

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Isothermal dialysate vs thermoneutral dialysate

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fixed reduction of dialysate temperature vs standard dialysate temperature

It is very uncertain whether fixed reduction of dialysate temperature changes discomfort rate compared with standard dialysate temperature (very low certainty).

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  Rate ratio 8.31 [1.86, 37.12]
  4 studies · 81 participants
  Very low

Fixed reduction of dialysate temperature vs standard dialysate temperature

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 268 participants
  GRADE not reported

Fixed reduction of dialysate temperature vs standard dialysate temperature

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fixed reduction of dialysate temperature vs standard dialysate temperature

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fixed reduction of dialysate temperature vs standard dialysate temperature

The review found no eligible studies for this question.

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Isothermal dialysate vs thermoneutral dialysate

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 17 participants
  GRADE not reported

Isothermal dialysate vs thermoneutral dialysate

• Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 133 participants
  GRADE not reported

Calcium channel blockers vs placebo/no treatment

Calcium channel blockers showed no clear difference in death compared with placebo/no treatment (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 0.82 [0.37, 1.82]
  12 studies · 792 participants
  Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 77 participants
  Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 175 participants
  Moderate

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 272 participants
  Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 191 participants
  Moderate

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 392 participants
  Very low