Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

251 questions · 255 findings · 24 reviews

No studies found 61 · 23.9%GRADE not reported 40 · 15.7%Very low 45 · 17.6%Low 56 · 22%Moderate 38 · 14.9%High 15 · 5.9%

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Bleeding: Number of days on which a significant bleeding event occurred3 · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in bleeding: Number of days on which a significant bleeding event… compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in mortality: Secondary to bleeding compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in bleeding: Numbers of patients with at least one significant bleeding… compared with higher transfusion threshold (20,000 or 30,000) (moderate certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in mortality: secondary to bleeding compared with higher transfusion threshold (20,000 or 30,000) (low certainty).

1 finding from 1 review