Findings

What do systematic reviews say?

3,584 questions · 3,695 findings · 567 reviews

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No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding

SAEs · participants with obesity

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding

Reoperation rate · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 240 participants
Very low

Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding

Body‐mass index (BMI) · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 265 participants
Moderate

Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding

Health related quality of life the Uniscale and the Symptom Distress Scale (SDS); Better indicated by lower values · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 250 participants
Very low

Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding

Comorbidities: diabetes · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Very low

Dual zinc + arginine dentifrice vs Control (regular fluoride) dentifrice

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether dual zinc + arginine dentifrice changes dentist-reported OLT hedonic rating (scale 1 to 9) compared with control (regular fluoride) dentifrice (very low certainty).

1 finding from 1 review

Interventions for managing halitosis 2019 · Cochrane All outcomes
mean 3 weeks
MD -2.0 [-2.19, -1.81]
1 study · 80 participants
Very low

Norfloxacin plus amphotericin B vs Amphotericin B

Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy

Norfloxacin plus amphotericin B showed no clear difference in oral candidiasis (present) compared with amphotericin B; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.38 [0.15, 1.0]
1 study · 106 participants
GRADE not reported

Norfloxacin plus amphotericin B vs Amphotericin B

Systemic fungal infection · Patients with cancer receiving chemotherapy and/or radiotherapy

Norfloxacin plus amphotericin B showed no clear difference in systemic fungal infection compared with amphotericin B; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.67 [0.2, 2.23]
1 study · 106 participants
GRADE not reported

Induction: liposomal amphotericin vs Amphotericin B

Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · adults with HIV and progressive disseminated histoplasmosis

Induction: liposomal amphotericin may leads to higher clinical success compared with amphotericin deoxycholate (low certainty).

1 finding from 1 review

Treating progressive disseminated histoplasmosis in people living with HIV 2020 · Cochrane Headline outcomes only
RR 1.46 [1.01, 2.11]
1 study · 80 participants
Low

Induction: liposomal amphotericin vs Amphotericin B

Death · adults with HIV and progressive disseminated histoplasmosis

Induction: liposomal amphotericin showed no clear difference in death compared with amphotericin deoxycholate (low certainty).

1 finding from 1 review

Treating progressive disseminated histoplasmosis in people living with HIV 2020 · Cochrane Headline outcomes only
RR 0.15 [0.02, 1.38]
1 study · 77 participants
Low

Induction: liposomal amphotericin vs Amphotericin B

Nephrotoxicity (safety population) · adults with HIV and progressive disseminated histoplasmosis

Induction: liposomal amphotericin leads to lower safety outcomes: nephrotoxicity compared with amphotericin deoxycholate (high certainty).

1 finding from 1 review

Treating progressive disseminated histoplasmosis in people living with HIV 2020 · Cochrane Headline outcomes only
RR 0.25 [0.09, 0.67]
1 study · 77 participants
High

Induction: liposomal amphotericin vs Amphotericin B

Safety outcomes: drug discontinuation · adults with HIV and progressive disseminated histoplasmosis

It is very uncertain whether induction: liposomal amphotericin changes safety outcomes: drug discontinuation compared with amphotericin deoxycholate (very low certainty).

1 finding from 1 review

Treating progressive disseminated histoplasmosis in people living with HIV 2020 · Cochrane Headline outcomes only
RR 0.23 [0.02, 2.38]
1 study · 77 participants
Very low

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women cured · women with urinary incontinence

It is very uncertain whether PFMT added to electrical stimulation changes number of women cured compared with electrical stimulation alone (excluding implanted electrodes) (very low certainty).

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
RR 2.06 [0.79, 5.38]
2 studies · 56 participants
Very low

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women reporting incontinence at 1 year or more after treatment (subjective) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Objective measure of urine leakage (e.g. pad test) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women experiencing pain ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Disease‐specific quality of life · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

General health status evaluation e.g. Short Form (SF)‐36 ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

All‐cause mortality · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes all‐cause mortality compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 238 participants
Very low