It is very uncertain whether tubeless PNL changes blood transfusion MCID: 10 per 1000 compared with standard PNL (very low certainty).
It is very uncertain whether tubeless PNL changes sepsis or fever MCID: 50 per 1000 compared with standard PNL (very low certainty).
It is very uncertain whether tubeless PNL changes readmission (first 30 days) MCID: 50 per 1000 compared with standard PNL (very low certainty).
Totally tubeless PNL showed no clear difference in severe adverse events MCID: 50 per 1000 compared with standard PNL (low certainty).
Thrombo‐aspiration alone showed no clear difference in functional independence at 3 months (mRS 0 to 2) (primary outcome) compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in successful reperfusion (mTICI 2b to 3) postprocedure compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in all‐cause mortality within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in intracranial hemorrhage on imaging at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in symptomatic intracranial hemorrhage at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).
Thrombo‐aspiration alone showed no clear difference in procedure‐related adverse events within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).
It is very uncertain whether ultrasound‐accelerated thrombolysis changes amputation rate compared with thrombolysis alone (very low certainty).
It is very uncertain whether ultrasound‐accelerated thrombolysis changes major bleeding compared with thrombolysis alone (very low certainty).
It is very uncertain whether ultrasound‐accelerated thrombolysis changes clinical success ‐ increase in ABI by at least 0.2 compared with thrombolysis alone (very low certainty).