Cochrane · systematic review · CD012607

Totally tubeless, tubeless, and tubed percutaneous nephrolithotomy for treating kidney stones

Wilhelm, K, Hein, S, Kunath, F, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

UrologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 42.9%Low 5 · 35.7%Moderate 3 · 21.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Tubeless PNL compared to standard PNL for treating kidney stones

Population: treating kidney stones
7 questions
OutcomeEffectEvidenceStatus / GRADE
Severe adverse events MCID: 50 per 1000
Tubeless PNL vs standard PNL
RR 1.53 [0.14, 16.46]2 studies · 46 participantsVery low
Downgraded: risk of bias, imprecision
Postoperative pain (day 1)
Tubeless PNL vs standard PNL
no estimate extracted4 studies · 186 participantsLow
Downgraded: risk of bias, inconsistency
Operating time (minutes) MCID: 15 min
Tubeless PNL vs standard PNL
no estimate extracted3 studies · 81 participantsModerate
Downgraded: risk of bias
Length of hospital stay (days) MCID: 0.5 days
Tubeless PNL vs standard PNL
no estimate extracted6 studies · 238 participantsLow
Downgraded: risk of bias, inconsistency
Blood transfusion MCID: 10 per 1000
Tubeless PNL vs standard PNL
RR 0.64 [0.16, 2.52]4 studies · 161 participantsVery low
Downgraded: risk of bias, imprecision
Sepsis or fever MCID: 50 per 1000
Tubeless PNL vs standard PNL
RR 0.5 [0.05, 4.75]2 studies · 82 participantsVery low
Downgraded: risk of bias, imprecision
Readmission (first 30 days) MCID: 50 per 1000
Tubeless PNL vs standard PNL
RR 1 [0.07, 14.21]1 study · 24 participantsVery low
Downgraded: risk of bias, imprecision

Totally tubeless PNL compared to standard PNL for treating kidney stones

Population: treating kidney stones
7 questions
OutcomeEffectEvidenceStatus / GRADE
Severe adverse events MCID: 50 per 1000
Totally tubeless PNL vs standard PNL
RR 0.49 [0.19, 1.25]2 studies · 174 participantsLow
Downgraded: risk of bias, imprecision
Postoperative pain (day 1)
Totally tubeless PNL vs standard PNL
no estimate extracted1 study · 50 participantsLow
Downgraded: risk of bias, imprecision
Operating time (minutes) MCID: 15 min
Totally tubeless PNL vs standard PNL
no estimate extracted2 studies · 174 participantsModerate
Downgraded: risk of bias, inconsistency
Length of hospital stay (days) MCID: 0.5 days
Totally tubeless PNL vs standard PNL
no estimate extracted4 studies · 274 participantsModerate
Downgraded: risk of bias
Blood transfusion MCID: 10 per 1000
Totally tubeless PNL vs standard PNL
RR 0.62 [0.26, 1.48]4 studies · 274 participantsVery low
Downgraded: risk of bias, imprecision
Sepsis or fever MCID: 50 per 1000
Totally tubeless PNL vs standard PNL
RR 0.33 [0.01, 7.97]1 study · 90 participantsLow
Downgraded: risk of bias, imprecision
Readmission (first 30 days) MCID: 50 per 1000
Totally tubeless PNL vs standard PNL
no estimate extracted1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision