Remission · people with newly diagnosed epilepsy
Summary of findings: oxcarbazepine showed no clear difference in time to achieve 12‐month remission (seizure‐free period) All… compared with phenytoin (secondary outcomes) (moderate certainty).
1 finding from 1 review
Time on allocated treatment (retention time) · people with focal or generalized seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Seizure freedom · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
50% responder rate · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects requiring withdrawal/discontinuation of study medication · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
Clobazam showed no clear difference in adverse effects requiring withdrawal/discontinuation of study… compared with phenytoin (low certainty).
1 finding from 1 review
Retention [ · people with focal or generalized seizures
Clobazam showed no clear difference in retention at 12 months compared with carbamazepine (low certainty).
1 finding from 1 review
Seizure freedom · people with focal or generalized seizures
Clobazam showed no clear difference in seizure freedom at 4 weeks compared with carbamazepine (low certainty).
2 findings from 1 review
50% responder rate · people with focal or generalized seizures
Clobazam showed no clear difference in 50% responder rate compared with carbamazepine (low certainty).
1 finding from 1 review
Adverse effects requiring withdrawal/discontinuation of study medication · people with focal or generalized seizures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time on allocated treatment (retention time) · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Retention [ · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma
Clobazam may leads to higher retention at 6 months (measured by the number of treatment failures… compared with phenytoin (low certainty).
1 finding from 1 review
Non‐cessation of seizures · patients with status epilepticus
Lorazepam IV probably leads to lower non‐cessation of seizures compared with diazepam IV (moderate certainty).
1 finding from 1 review
Non‐cessation of seizures · patients with status epilepticus
Diazepam gel probably leads to lower non‐cessation of seizures compared with placebo gel (moderate certainty).
1 finding from 1 review
Adverse effects · patients with status epilepticus
Diazepam gel showed no clear difference in adverse effects compared with placebo gel (moderate certainty).
1 finding from 1 review
Requirement for ventilatory support · patients with status epilepticus
Lorazepam IV showed no clear difference in requirement for ventilatory support compared with diazepam IV (low certainty).
1 finding from 1 review
Adverse effects · patients with status epilepticus
1 finding from 1 review
Continuation of status requiring a different drug or general anaesthesia · patients with status epilepticus
Lorazepam IV probably leads to lower continuation of status requiring a different drug or general… compared with diazepam IV (moderate certainty).
1 finding from 1 review
Death · patients with status epilepticus
1 finding from 1 review
Non‐cessation of seizures · patients with status epilepticus
Lorazepam IV showed no clear difference in non‐cessation of seizures compared with diazepam plus phenytoin IV (low certainty).
1 finding from 1 review
Adverse effects · patients with status epilepticus
Lorazepam IV showed no clear difference in adverse effects compared with diazepam plus phenytoin IV (moderate certainty).
1 finding from 1 review