Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,773 questions · 1,817 findings · 212 reviews · Headline outcomes only

No studies found 383 · 21.1%GRADE not reported 192 · 10.6%Very low 472 · 26%Low 444 · 24.4%Moderate 228 · 12.5%High 98 · 5.4%

Regional anaesthesia vs conventional pain control

Knee Society Score compared to preoperative value · people undergoing total knee replacement
2 findings from 1 review

Annual chest x‐ray screening vs usual care (no regular screening)

Mortality: lung cancer · Patients with lung cancer

Annual chest x‐ray screening showed no clear difference in lung cancer mortality at 6 years of compared with usual care (no regular screening) (high certainty).

2 findings from 1 review

Annual chest x‐ray screening vs usual care (no regular screening)

Deaths from all causes (excluding deaths from PLCO cancers) · Patients with lung cancer

Annual chest x‐ray screening showed no clear difference in deaths from all causes (excluding deaths from PLCO cancers) compared with usual care (no regular screening) (high certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite and possible Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite and possible Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Awareness: definite Postoperative interview · patients with prevention of recall of events during surgery

Anaesthesia depth monitors (BIS) showed no clear difference in awareness: definite Postoperative interview compared with standard clinical and electronic monitoring (low certainty).

1 finding from 1 review

Anaesthesia depth monitors (BIS) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Percutaneous patellar osteosynthesis vs open surgery

Observer‐rated measures of knee function Knee function scores (see comment) · adults with fractures of the patella

It is very uncertain whether percutaneous patellar osteosynthesis changes observer‐rated measures of knee function Knee function scores (see… compared with open surgery (very low certainty).

1 finding from 1 review