Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

643 questions · 693 findings · 156 reviews

No studies found 177 · 25.5%GRADE not reported 100 · 14.4%Very low 144 · 20.8%Low 139 · 20.1%Moderate 106 · 15.3%High 27 · 3.9%

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Costs: treatment/operation time · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

It is very uncertain whether rubber dam isolation and moisture control (alone or with saliva… changes costs: treatment/operation time compared with cotton rolls (with or without saliva aspiration) (very low certainty).

1 finding from 1 review

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Clinical evaluation of restoration's quality · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    6, 12, 18 months · Non-carious cervical lesions (composite restoration)
    Loguercio 2015: no significant differences (P>0.05) in marginal staining and marginal adaptation of NCCL restorations between rubber dam and cotton rolls/retraction cords at 6, 12 and 18 months.
    1 study · 30 participants
    GRADE not reported

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    Non-carious cervical lesions (composite restoration)
    Evidence did not support higher acceptance/preference for rubber dam than cotton rolls (P = 0.85 from binomial test on 28 participants; very low-certainty evidence) (Loguercio 2015).
    1 study · 28 participants
    Very low

Summary of findings table ‐ Treatment of clinical and electrographic seizures vs treatment of clinical seizures alone

Mortality before hospital discharge · neonates

Summary of findings table ‐ Treatment of clinical and electrographic… showed no clear difference in mortality before hospital discharge compared with treatment of clinical seizures alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Treatment of clinical and electrographic seizures vs treatment of clinical seizures alone

Proportion of infants who develop epilepsy post‐discharge · neonates

Summary of findings table ‐ Treatment of clinical and electrographic… showed no clear difference in proportion of infants who develop epilepsy post‐discharge compared with treatment of clinical seizures alone (low certainty).

1 finding from 1 review

Interdental brushing plus toothbrushing vs Toothbrushing alone

Side effects · Adults, 16 years and older (dentate)
2 findings from 2 reviews · compare the 2 reviews

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT

Any adverse effect related to aPDT · Adults (> 18 years) with peri-implant mucositis, receiving active treatment

The review found no eligible studies for this question.

1 finding from 1 review

Pexastimogene devacirepvec (Pexa‐Vec) plus best supportive care vs best supportive care

Overall survival (absolute effect size estimates based on survival rate at 12 months) · participants with advanced hepatocellular carcinoma

It is very uncertain whether pexastimogene devacirepvec (Pexa‐Vec) plus best supportive care changes overall survival (absolute effect size estimates based on survival… compared with best supportive care alone (very low certainty).

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Any adverse effect related to aPDT · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
1 finding from 1 review

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Need for vitrectomy · proliferative diabetic retinopathy

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… may leads to lower need for vitrectomy compared with PRP alone (low certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection in women with dense breasts: cohort studies · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in incremental cancer detection in women with dense breasts: RCT compared with mammography alone (high certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental detection of invasive cancers · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in incremental detection of invasive cancers compared with mammography alone (low certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection for women with non‐dense breasts: cohort studies · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to higher incremental cancer detection for women with non‐dense breasts: RCT compared with mammography alone (moderate certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection: cohort studies · s of women with dense and non‐dense breasts

Mammography in combination with breast ultrasonography leads to higher incremental cancer detection: RCT compared with mammography alone (high certainty).

2 findings from 1 review