Non‐selective NSAIDs vs selective cyclo‐oxygenase‐2 inhibitors
Global assessment of treatment success · acute gout
1 finding from 1 review
- no estimate extractedStudies not reportedModerate
Findings
What do systematic reviews say?
1,036 questions · 1,100 findings · 261 reviews
No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%
NSAIDs vs glucocorticoids
Global assessment of treatment success · acute gout
NSAIDs showed no clear difference in patients' global assessment of treatment success at day 3 to 4 compared with glucocorticoids (moderate certainty).
1 finding from 1 review
- RR 0.92 [0.7, 1.22]Studies not reportedModerate
NSAIDs vs placebo
Participants' global assessment of treatment: not measured№. of participants: 30 (1 RCT) · acute gout
1 finding from 1 review
- no estimate extractedStudies not reportedLow
Vitamin C vs allopurinol
Participant global assessment · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Skim milk enriched with GMP/G600 vs skim milk & lactose powder
Global assessment of treatment success · people with chronic gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo
Partcipant assessment of success · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher partcipant assessment of success compared with placebo (moderate certainty).
1 finding from 1 review
- RR 19.45 [8.6, 43.99]4 studies · 575 participantsModerate
Summary of Findings Table ‐ IncobotulinumtoxinA 20U vs placebo
Participant assessment of success by analysing scores and scales ‐ 4 weeks · glabellar lines
Summary of Findings Table ‐ IncobotulinumtoxinA 20U probably leads to higher participant assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 66.57 [13.5, 328.28]2 studies · 547 participantsModerate
Summary of Findings Table ‐ IncobotulinumtoxinA 20U vs placebo
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ IncobotulinumtoxinA 20U probably leads to higher physician assessment of success by analysing scores and scales compared with placebo (moderate certainty).
1 finding from 1 review
- RR 134.62 [19.05, 951.45]2 studies · 547 participantsModerate
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs OnabotulinumtoxinA 20U
Participant assessment of success by analysing scores and scales ‐ 4 weeks · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in participant assessment success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).
1 finding from 1 review
- RR 1 [0.92, 1.08]1 study · 388 participantsHigh
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs OnabotulinumtoxinA 20U
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in physician assessment of success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 20U (high certainty).
1 finding from 1 review
- RR 1.01 [0.95, 1.06]1 study · 388 participantsHigh
Summary of Findings Table ‐ IncobotulinumtoxinA 24U vs OnabotulinumtoxinA 24U
Participant global assessment of success Not measured · glabellar lines
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Summary of Findings Table ‐ IncobotulinumtoxinA 24U vs OnabotulinumtoxinA 24U
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ IncobotulinumtoxinA 24U showed no clear difference in physician assessment of success by analysing scores and scales ‐ 4… compared with onabotulinumtoxinA 24U (low certainty).
1 finding from 1 review
- RR 1.01 [0.96, 1.05]1 study · 381 participantsLow
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U vs placebo
Participant assessment of success by analysing scores and scales ‐ 4 weeks · glabellar lines
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U probably leads to higher participant assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 21.1 [11.31, 39.34]2 studies · 683 participantsModerate
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U vs placebo
Physician assessment of success by analysing scores and scales ‐ 4 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ DaxibotulinumtoxinA 40U probably leads to higher physician assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 23.4 [12.56, 43.61]2 studies · 683 participantsModerate
Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo
Physician assessment of success · glabellar lines
Summary of Findings Table ‐ OnabotulinumtoxinA 20U probably leads to higher physician assessment of success compared with placebo (moderate certainty).
1 finding from 1 review
- RR 17.1 [10.07, 29.05]7 studies · 1339 participantsModerate
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Participant assessment of success by analysing scores and scales ‐ 20 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U leads to higher participant assessment of success by analysing scores and scales ‐… compared with placebo (high certainty).
1 finding from 1 review
- RR 5.33 [1.67, 16.99]1 study · 300 participantsHigh
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Physician assessment of success · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U probably leads to higher physician assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 15.78 [8.75, 28.45]7 studies · 1060 participantsModerate
Intervention not reported
Overall communication skills Different scales used by different studies: total scores vary across communication items or average score on a Likert scale Based on assessments occurring immediately and up to 12 months after intervention delivery · pre‐registration medical students
1 finding from 1 review
- Interventions for improving medical students' interpersonal communication in medical consultations 2021 · Cochrane Headline outcomes onlyno estimate extracted18 studies · 1356 participantsLow
Intervention not reported
Relationship building/rapport Different scales used by different studies: average empathy score across several items or average score on a Likert scale Based on assessments occurring immediately and up to 12 months after intervention delivery · pre‐registration medical students
1 finding from 1 review
- Interventions for improving medical students' interpersonal communication in medical consultations 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 176 participantsModerate
Intervention not reported
Overall communication skills Different scales used across studies: total scores vary across communication items or average score on a Likert scale Based on assessments occurring immediately and up to 12 months after intervention delivery · pre‐registration medical students
1 finding from 1 review
- Interventions for improving medical students' interpersonal communication in medical consultations 2021 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 502 participantsModerate