Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ nasal trauma · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ nasal trauma compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ abdominal overdistention · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ abdominal overdistention compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

Telerehabilitation vs self‐training

Vision‐related patient‐reported outcome measurement at 6 months (the greater the score, the better) · people with any eye disease including optic nerve disease, age‐related macular degeneration, retinopathy of prematurity, retinitis…
1 finding from 1 review

Telerehabilitation vs self‐training

Clinical measures, such as reading speed or reading acuity at 6 months · people with any eye disease including optic nerve disease, age‐related macular degeneration, retinopathy of prematurity, retinitis…

The review found no eligible studies for this question.

1 finding from 1 review

Telerehabilitation vs self‐training

Technical difficulties · people with any eye disease including optic nerve disease, age‐related macular degeneration, retinopathy of prematurity, retinitis…

It is very uncertain whether telerehabilitation changes technical difficulties with the intervention at 6 months compared with self‐training (very low certainty).

1 finding from 1 review

Telerehabilitation vs self‐training

Device abandonment rate at 6 months · people with any eye disease including optic nerve disease, age‐related macular degeneration, retinopathy of prematurity, retinitis…

It is very uncertain whether telerehabilitation changes device abandonment rate at 6 months compared with self‐training (very low certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Breakthrough pain · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus probably leads to lower breakthrough pain compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Caesarean delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in caesarean delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Automated mandatory bolus vs basal infusion

Instrumental delivery during labour epidural analgesia · term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia

Automated mandatory bolus showed no clear difference in instrumental delivery during labour epidural analgesia compared with basal infusion (moderate certainty).

1 finding from 1 review

Vitamin D vs placebo

Rate of exacerbations requiring systemic corticosteroids · children and adults with predominantly mild to moderate asthma

Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations treated… compared with placebo (high certainty).

1 finding from 1 review

Vitamin D vs placebo

Patients with severe exacerbations (requiring hospitalisation or ER visit) · children and adults with predominantly mild to moderate asthma

Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Vitamin D vs placebo

Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma

Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).

1 finding from 1 review