new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF had a 28% preventative fraction at 24 months; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Quality of life · People aged 12 years and over with painful TMD lasting 3 months or longer
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in pain intensity at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under remineralizing conditions, nHA produced significantly more remineralization than the negative control (MD 350, 95% CI 179 to 521; very low certainty).
2 findings from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Relaxation showed no clear difference in pain intensity compared with occlusal (oral) appliance; GRADE not reported.
1 finding from 1 review
Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomesTreatment completion · Adolescents (12-19 years)
Not pooled. Wahlund 2015: MD 3.70 (95% CI -1.21 to 8.61), n=57 (relaxation 28, appliance 29); Wahlund 2003: MD not reported, n=83 (relaxation 41, appliance 42). Both studies were in adolescents; the occlusal appliance…
2 studies · 140 participants
GRADE not reported
Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) may leads to lower psychological distress at follow-up compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Additional physical symptoms · People aged 12 years and over with painful TMD lasting 3 months or longer
The review found no eligible studies for this question.
1 finding from 1 review
Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in disability caused by pain at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Complications and side effects · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Diagnostic accuracy for root caries detection · Dental radiographic/intraoral images of human teeth (X-ray and photographic)
One study reported machine-learning accuracy for root caries detection (97.1%, support vector machine); not pooled and not graded.
1 finding from 1 review
MRONJ (incidence proportion) · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
In both study arms, no case of postoperative MRONJ was observed (700 participants; 1 RCT); effect not estimable.
1 study · 700 participants
GRADE not reported
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under demineralizing conditions, nHA allowed significantly more enamel demineralization than NaF (MD 1625, 95% CI 553 to 2697; very low certainty).
2 findings from 1 review
Live birth rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ongoing pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in ongoing pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Miscarriage per clinical pregnancy · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in miscarriage rate per clinical pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review
Clinical pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone may leads to higher clinical pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Multiple pregnancy rate · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in multiple pregnancy rate compared with placebo/no treatment (low certainty).
1 finding from 1 review
Adverse events, OHSS, preterm delivery, congenital anomaly · women with gonadotropin plus oral (clomiphene citrate or letrozole) stimulation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Live birth or ongoing pregnancy · women with oral (clomiphene citrate or letrozole) stimulation
Progesterone showed no clear difference in live birth rate/ongoing pregnancy compared with placebo/no treatment (low certainty).
1 finding from 1 review