Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,556 questions · 2,794 findings · 119 reviews · Oral Health

No studies found 489 · 17.5%GRADE not reported 1,719 · 61.5%Very low 399 · 14.3%Low 128 · 4.6%Moderate 58 · 2.1%High 1 · 0%

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole,… led to lower oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Antifungal drugs not absorbed from GI tract

Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract showed no clear difference in toxicity (adverse events probably due to drug) compared with antifungal drugs not absorbed from GI tract; GRADE not reported.

1 finding from 1 review

Lingualised teeth (maxillary anatomic + mandibular non-anatomic; lingualised occlusion scheme) vs Zero-degree teeth (non-anatomic, cuspless)

Number of denture adjustments required · Edentulous adult patients requiring complete dentures
1 finding from 1 review

Lingualised teeth (maxillary anatomic + mandibular non-anatomic; lingualised occlusion scheme) vs Zero-degree teeth (non-anatomic, cuspless)

Patient perceived satisfaction (denture preference) · Edentulous adult patients requiring complete dentures

Lingualised teeth (maxillary anatomic + mandibular non-anatomic;… led to higher patient perceived satisfaction (denture preference) compared with zero-degree teeth (non-anatomic, cuspless); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with eating with denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with eating with denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with appearance of denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with appearance of denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Overall denture satisfaction (0-10 scale) · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) led to lower overall denture satisfaction (0-10 scale) compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

3 findings from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with speech with denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with speech with denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Altered chin or lower lip skin sensation (binary) · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) led to lower morbidity: altered sensation of the lower lip and chin compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with lower denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with lower denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review

Preprosthetic surgery for a conventional denture (PPS) vs Implant retained overdenture (dental implants) (IRO)

Dissatisfied with retention of denture · Edentulous patients requiring improved denture retention

Preprosthetic surgery for a conventional denture (PPS) showed no clear difference in dissatisfied with retention of denture compared with implant retained overdenture (dental implants) (IRO); GRADE not reported.

1 finding from 1 review