Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Botulinum toxin vs surgery

Improved or corrected strabismusa at 6 or 12 months · adults and children with strabismus

Botulinum toxin may leads to lower improved or corrected strabismusa at 6 or 12 months compared with surgery (low certainty).

1 finding from 1 review

Botulinum toxin vs surgery

Proportion of participants who achieved binocular single vision at 6 or 12 months · adults and children with strabismus

Botulinum toxin showed no clear difference in proportion of participants who achieved binocular single vision at 6… compared with surgery (low certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Perioperative mortality · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in perioperative mortality (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Myocardial infarction (0 to 30 days) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in myocardial infarction (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Renal impairment (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in renal impairment (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Limb loss (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in limb loss (within 1 month after operation) compared with no RIPC (low certainty).

1 finding from 1 review