Findings

What do systematic reviews say?

3,801 questions · 4,079 findings · 473 reviews

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No studies found 669 · 16.4%GRADE not reported 852 · 20.9%Very low 738 · 18.1%Low 903 · 22.1%Moderate 716 · 17.6%High 201 · 4.9%

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L or less) · general population over 2 years of age

Staple foods fortified with vitamin A plus other micronutrients probably leads to lower subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L… compared with same unfortified staple foods (moderate certainty).

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
RR 0.27 [0.16, 0.49]
3 studies · 923 participants
Moderate

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Death (all‐cause) · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Mental development · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cognitive function and motor skill development · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cretinism · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Hypothyroidism · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse effects (RCT) · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Intervention not reported

Urinary iodine concentration (RCT) · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2032 participants
Moderate

Intervention not reported

Urinary iodine concentration (non‐RCT) · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
262 participants
Very low

Intervention not reported

Thyroid‐stimulating hormone concentration · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serum thyroglobulin concentration · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Goitre prevalence (RCT) · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Very low

Intervention not reported

Goitre prevalence (non‐RCT) · all populations, including pregnant women, from any country

It is very uncertain whether the intervention changes goitre prevalence (non‐RCT) (very low certainty).

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
OR 1.6 [0.6, 4.31]
83 participants
Very low

Intervention not reported

Physical development measures (non‐RCT) · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

a. Weight · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
83 participants
Very low

Intervention not reported

b. Height assessment tool not reported · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
83 participants
Very low

Intervention not reported

c. Weight‐for‐age computed from weight and age values · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
83 participants
Very low

Intervention not reported

d. Height‐for‐age computed from height and age values · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
83 participants
Very low

Intervention not reported

e. Weight‐for‐height computed from weight and height values · all populations, including pregnant women, from any country

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
83 participants
Very low