Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Combinations of conservative treatments vs no treatment, sham treatment or verbal/written instruction

Number of participants experiencing muscle‐related adverse events: e.g. soreness, discomfort, cramps, pain · men with urinary incontinence following prostate surgery

It is very uncertain whether combinations of conservative treatments changes number of participants experiencing muscle‐related adverse events:… compared with no treatment, sham treatment or verbal/written instruction (very low certainty).

1 finding from 1 review

Pelvic floor muscle training (PFMT) plus biofeedback vs no treatment, sham treatment or verbal/written instruction

Number of participants experiencing surface or skin‐related adverse events: e.g. skin reactions, bruising, hypersensitivity to gel · men with urinary incontinence following prostate surgery
1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants with IOP control (higher number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

Phacoemulsification may leads to higher proportion of participants with IOP control (higher number of events… compared with laser peripheral iridotomy (low certainty).

1 finding from 1 review

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Treatment failure · preterm infants receiving nasal CPAP

Bubble may leads to lower treatment failure compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Mortality before hospital discharge · preterm infants receiving nasal CPAP

Bubble showed no clear difference in all‐cause mortality before hospital discharge compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Pneumothorax · preterm infants receiving nasal CPAP

Bubble showed no clear difference in pneumothorax compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Moderate‐severe nasal injury · preterm infants receiving nasal CPAP

Bubble probably leads to higher moderate‐severe nasal injury compared with ventilator or Infant Flow Driver nasal continuous positive airway… (moderate certainty).

1 finding from 1 review

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Bronchopulmonary dysplasia · preterm infants receiving nasal CPAP

Bubble showed no clear difference in bronchopulmonary dysplasia compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

Higher parental / maternal education vs Lower parental education (reference)

Oral health-related quality of life · Adolescents (10-19 years)

Higher parental education is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Children from families with high income, parental education and family economy had better OHRQoL [42].
    Studies not reported
    GRADE not reported