Findings

What do systematic reviews say?

2,556 questions · 2,794 findings · 119 reviews · All outcomes

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No studies found 489 · 17.5%GRADE not reported 1,719 · 61.5%Very low 399 · 14.3%Low 128 · 4.6%Moderate 58 · 2.1%High 1 · 0%

Brushing vs Association of brushing and effervescent tablets

Total anaerobes (colony forming units, log-transformed) · Maxillary complete denture (CD) wearers

Brushing led to higher total anaerobes (colony forming units, log-transformed) compared with association of brushing and effervescent tablets; GRADE not reported.

1 finding from 1 review

Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
MD 5.64 [4.86, 6.42]
1 study · 18 participants
GRADE not reported

Prophylactic aciclovir (oral or intravenous) vs placebo

Adverse effects · Patients being treated for cancer (predominantly haematological malignancies)

1 finding from 1 review

Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer 2009 · Cochrane All outcomes
Adverse effects were reported in nine trials. Diagnosis was by evaluation of clinical signs and symptoms (e.g. rash, neurological impairment) and by laboratory tests including renal and hepatic function. None of the…
9 studies
GRADE not reported

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Patient acceptability of treatment and its side effects · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Quality of life (validated questionnaire) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
No data were available for this patient-reported outcome in the single included trial.
0 studies
No studies found

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Instrumental assessment: nasalance score (nasometry and pressure-flow measure) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
Nasalance score by nasometry and pressure-flow measure: the single included trial (Ysunza 2001) provided no data for this outcome.
0 studies
No studies found

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Change in probing pocket depth (PPD) · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.04 [-0.19, 0.27]
1 study · 50 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Patient acceptability of treatment and its side effects · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Self-esteem (Piers-Harris self-concept scale) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
No data were available for this patient-reported outcome in the single included trial.
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Instrumental assessment: velopharyngeal complete closure and gap size (videonasopharyngoscopy and multiview videofluoroscopy) · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
3 months post-operatively
Complete closure occurred in 32 (86%) of the participants in group 1 (MIPP) and in 31 (89%) in group 2, P > 0.05. After eliminating the nine patients with residual velopharyngeal insufficiency, the post-operative gap…
1 study · 72 participants
GRADE not reported

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Tooth loss · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Tooth loss · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.40 [0.05, 0.75]
1 study · 50 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
Minimum 3 months (planned)
no estimate extracted
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Adverse effect: failure of muscle fusion in the region of the cleft after surgery · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
There were no reports of failure of muscle fusion after surgery.
1 study · 72 participants
GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Adverse effect: unacceptable nasal resonance after repair · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
The trial report provided no information on this adverse event; no information on adverse events or serious complications was reported.
0 studies
No studies found

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Adverse effect: obstructive sleep apnoea or airway compromise · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
The investigators stated that none of the participants reported obstructive sleep apnoea after the interventions.
1 study · 72 participants
GRADE not reported

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

Perceptual speech assessment: residual post-operative velopharyngeal insufficiency · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate

1 finding from 1 review

Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
3 months post-operatively
Five (14%) of the participants in group 1 (MIPP) and four (11%) in group 2 had residual post-operative velopharyngeal insufficiency, P > 0.05. The report provided no details on post-operative speech assessment other…
1 study · 72 participants
GRADE not reported

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Change in probing pocket depth (PPD) · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.01 [-0.20, 0.22]
1 study · 50 participants
GRADE not reported

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal interventions for periodontitis in adults 2008 · Cochrane All outcomes
2 years
MD 0.38 [0.04, 0.72]
1 study · 50 participants
GRADE not reported