Findings

What do systematic reviews say?

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

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No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Intervention not reported

Health‐related quality of life Multiple different outcome measures used EQ‐5D and EQ‐5D VAS (9 and 26 weeks) (Batterham 2014) SF‐36 PCS and MCS (8 and 26 weeks) (Elliott 2011) · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low

Intervention not reported

Withdrawals Participant withdrawal following randomization before or during receipt of the intervention because of consent or medical reason · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 341 participants
Low

Intervention not reported

Adherence Participant completion of the intervention as described in the trial method · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Intervention not reported

Mortality Death at any point during the trial duration · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 483 participants
Low

Intervention not reported

Loss to · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 483 participants
Low

Intervention not reported

Other adverse events Non‐mortality · adult survivors of critical illness

1 finding from 1 review

Exercise rehabilitation following intensive care unit discharge for recovery from critical illness 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 376 participants
Low

Intervention not reported

Changes in objective sleep variables (SEI, SFI, REM sleep) · critically ill patients

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 403 participants
Very low

Intervention not reported

Length of ICU stay · critically ill patients

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Intervention not reported

Subjective sleep quality or quantity · critically ill patients

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 1220 participants
Low

Intervention not reported

Risk of delirium · critically ill patients

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 177 participants
Low

Intervention not reported

Any adverse event · critically ill patients

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 72 participants
Very low

Intervention not reported

Mortality · critically ill patients

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Economic outcomes · critically ill patients

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for sleep promotion in the intensive care unit 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nurse‐led titration vs usual care

Hospital admissions · people with heart failure with reduced ejection fraction

Nurse‐led titration leads to lower all‐cause hospital admissions compared with usual care (high certainty).

1 finding from 1 review

Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
RR 0.8 [0.72, 0.88]
4 studies · 560 participants
High

Nurse‐led titration vs usual care

Heart failure hospitalisation (RR) · people with heart failure with reduced ejection fraction

Nurse‐led titration probably leads to lower heart failure‐related hospital admissions compared with usual care (moderate certainty).

1 finding from 1 review

Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
RR 0.51 [0.36, 0.72]
4 studies · 642 participants
Moderate

Nurse‐led titration vs usual care

All‐cause mortality · people with heart failure with reduced ejection fraction

Nurse‐led titration probably leads to lower all‐cause mortality compared with usual care (moderate certainty).

1 finding from 1 review

Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
RR 0.66 [0.48, 0.92]
6 studies · 902 participants
Moderate

Nurse‐led titration vs usual care

All‐cause event‐free survival · people with heart failure with reduced ejection fraction

Nurse‐led titration probably leads to lower all‐cause event‐free survival compared with usual care (moderate certainty).

1 finding from 1 review

Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
RR 0.6 [0.46, 0.77]
3 studies · 370 participants
Moderate

Nurse‐led titration vs usual care

Proportion reaching target dose of medications · people with heart failure with reduced ejection fraction

Nurse‐led titration may leads to higher proportion reaching target dose of medications compared with usual care (low certainty).

1 finding from 1 review

Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
RR 1.99 [1.61, 2.47]
5 studies · 966 participants
Low

Intervention not reported

Pain (at study completion) WOMAC (VAS or NRS) from 0 to 20; lower scores mean reduced pain · People with hip or knee osteoarthritis

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 313 participants
Low

Intervention not reported

Physical function (at study completion) WOMAC (self administered health status measure) from 0 to 68; lower scores mean better function · People with hip or knee osteoarthritis

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 310 participants
Low