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What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Recombinant human growth hormone vs placebo or no intervention

Measures of renal function: change in TmP/GFR · children with X‐linked hypophosphataemia

It is very uncertain whether summary of findings ‐ recombinant growth hormone changes measures of renal function: change in TmP/GFR compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Recombinant human growth hormone vs placebo or no intervention

Body proportions: sitting height SDS · children with X‐linked hypophosphataemia

Summary of findings ‐ recombinant growth hormone showed no clear difference in body proportions: sitting height SDS compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Enteral tube feeding vs intravenous fluids

Successful insertion of intravenous fluid/enteral tube fluid at first attempt · health problem or population

Summary of findings table ‐ Enteral tube feeding probably leads to higher successful insertion of intravenous fluid/enteral tube fluid at… compared with intravenous fluids (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Enteral tube feeding vs intravenous fluids

Change in modality of fluid therapy · health problem or population

Summary of findings table ‐ Enteral tube feeding probably leads to lower change in modality of fluid therapy compared with intravenous fluids (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Enteral tube feeding vs intravenous fluids

Local complications (overall): IV line bruising, soreness, infection, epistaxis, nasal trauma, others · health problem or population

Summary of findings table ‐ Enteral tube feeding showed no clear difference in local complications (overall): IV line bruising, soreness,… compared with intravenous fluids (moderate certainty).

1 finding from 1 review