Overall survival (OS) · People with advanced non‐small cell lung cancer
Combined immune checkpoint inhibitors (ICIs) probably leads to lower overall Survival (OS) compared with chemotherapy (moderate certainty).
1 finding from 1 review
Progression‐free survival · People with advanced non‐small cell lung cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall response rate (OSR) · People with advanced non‐small cell lung cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Grades 3 and 4 adverse events · People with advanced non‐small cell lung cancer
Combined immune checkpoint inhibitors (ICIs) showed no clear difference in adverse Events grade 3 to 4 compared with chemotherapy (low certainty).
1 finding from 1 review
Outcomes and · adults with arrhythmias undergoing catheter ablation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Thromboembolic events · adults with arrhythmias undergoing catheter ablation
It is very uncertain whether interrupted changes thromboembolic events compared with uninterrupted anticoagulation therapy (very low certainty).
1 finding from 1 review
Major bleeding · adults with arrhythmias undergoing catheter ablation
Interrupted showed no clear difference in major bleeding compared with uninterrupted anticoagulation therapy (low certainty).
1 finding from 1 review
Composite endpoint of thromboembolic events (stroke or systemic embolism), major bleeding events, and all‐cause mortality · adults with arrhythmias undergoing catheter ablation
Interrupted may leads to lower composite endpoint of thromboembolic events (stroke or systemic… compared with uninterrupted anticoagulation therapy (low certainty).
1 finding from 1 review
Minor bleeding · adults with arrhythmias undergoing catheter ablation
It is very uncertain whether interrupted changes minor bleeding compared with uninterrupted anticoagulation therapy (very low certainty).
1 finding from 1 review
All‐cause mortality · adults with arrhythmias undergoing catheter ablation
Interrupted showed no clear difference in all‐cause mortality compared with uninterrupted anticoagulation therapy (low certainty).
1 finding from 1 review
Asymptomatic thromboembolic events · adults with arrhythmias undergoing catheter ablation
It is very uncertain whether interrupted changes asymptomatic thromboembolic events compared with uninterrupted anticoagulation therapy (very low certainty).
1 finding from 1 review
Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
The review found no eligible studies for this question.
1 finding from 1 review
Success rate at 1 year · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
It is very uncertain whether mineral trioxide aggregate (MTA) changes success rate at 1 year compared with root repair material (RRM) (very low certainty).
1 finding from 1 review
RR 1.00 [0.94, 1.07]
2 studies
Very low
Success rate (radiographically‐assessed healing of cyst healing based on the Neer/Cole rating system) · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
Mineral trioxide aggregate (MTA) showed no clear difference in success rate at 2 years compared with intermediate restorative material (IRM); GRADE not reported.
1 finding from 1 review
RR 1.05 [0.92, 1.20]
1 study
GRADE not reported
Success rate at 1 year · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
It is very uncertain whether mineral trioxide aggregate (MTA) changes success rate at 1 year compared with super ethoxybenzoic acid (Super-EBA) (very low certainty).
1 finding from 1 review
RR 1.03 [0.96, 1.10]
1 study
Very low
Adverse events · Patients needing retrograde filling in root canal therapy (orthograde root canal filling or retreatment not possible; periapical surgery…
The review found no eligible studies for this question.
1 finding from 1 review
Symptomatic VTE · ambulatory cancer patients receiving chemotherapy
DOAC showed no clear difference in symptomatic VTE compared with placebo (low certainty).
1 finding from 1 review
Symptomatic PE · ambulatory cancer patients receiving chemotherapy
Low‐molecular‐weight heparin probably leads to lower symptomatic PE compared with no thromboprophylaxis (moderate certainty).
1 finding from 1 review
Symptomatic DVT · ambulatory cancer patients receiving chemotherapy
Low‐molecular‐weight heparin leads to lower symptomatic DVT compared with no thromboprophylaxis (high certainty).
1 finding from 1 review