Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Massage vs usual care

Pain VAS for pain ( · people with postburn pruritus

Massage therapy showed no clear difference in pain VAS for pain ( compared with standard care (low certainty).

1 finding from 1 review

Extracorporeal shockwave therapy vs sham

Change in burn‐related pruritus (VAS) ( · people with postburn pruritus

Extracorporeal shock wave therapy showed no clear difference in change in burn‐related pruritus NRS ( compared with sham (low certainty).

1 finding from 1 review

Doxepin cream vs oral antihistamine

Somnolence · people with postburn pruritus

It is very uncertain whether doxepin cream changes adverse events (somnolence) compared with oral antihistamine (very low certainty).

1 finding from 1 review

Extracorporeal shockwave therapy vs sham

Pain Pressure pain threshold (PPT) ( · people with postburn pruritus

Extracorporeal shock wave therapy may leads to higher pain Pressure pain threshold (PPT) ( compared with sham (low certainty).

1 finding from 1 review

Gabapentin vs cetirizine (antihistamine)

Change in burn‐related pruritus (VAS) ( · people with postburn pruritus

Gabapentin showed no clear difference in change in burn‐related pruritus (VAS) ( compared with cetirizine (antihistamine) (low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes non‐surgical therapy for recurrent or persistent diseaseRadiation… compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review