Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Intervention not reported

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Improvement in acne severity assessed by a decrease in total inflammatory lesion count, measured in participants who were treated for a minimum period of 16 weeks (Changes from baseline in total inflammatory lesion count and number of participants... · participants with moderate and severe acne
1 finding from 1 review

Intervention not reported

Frequency of serious adverse effects 20 to 24 weeks · participants with moderate and severe acne

It is very uncertain whether the intervention changes frequency of serious adverse effects 20 to 24 weeks (very low certainty).

1 finding from 1 review

Intervention not reported

Improvement in acne severity assessed by physician's global evaluation 20 to 24 weeks · participants with moderate and severe acne
1 finding from 1 review