Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,730 questions · 18,059 findings · 1,282 reviews

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Extracorporeal shockwave therapy vs sham

Change in burn‐related pruritus (VAS) ( · people with postburn pruritus

Extracorporeal shock wave therapy showed no clear difference in change in burn‐related pruritus NRS ( compared with sham (low certainty).

1 finding from 1 review

Doxepin cream vs oral antihistamine

Somnolence · people with postburn pruritus

It is very uncertain whether doxepin cream changes adverse events (somnolence) compared with oral antihistamine (very low certainty).

1 finding from 1 review

Extracorporeal shockwave therapy vs sham

Pain Pressure pain threshold (PPT) ( · people with postburn pruritus

Extracorporeal shock wave therapy may leads to higher pain Pressure pain threshold (PPT) ( compared with sham (low certainty).

1 finding from 1 review

Gabapentin vs cetirizine (antihistamine)

Change in burn‐related pruritus (VAS) ( · people with postburn pruritus

Gabapentin showed no clear difference in change in burn‐related pruritus (VAS) ( compared with cetirizine (antihistamine) (low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes non‐surgical therapy for recurrent or persistent diseaseRadiation… compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review