Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening

All‐cause mortality ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer

Lung cancer screening with chest radiography +/‐ sputum cytology showed no clear difference in all‐cause mortality ‐ Annual chest x‐ray plus 4‐monthly cytology… compared with less intense screening (high certainty).

1 finding from 1 review

Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening

Lung cancer 5‐year survival ‐ More frequent chest x‐ray screening versus less frequent screening · Patients with lung cancer

Lung cancer screening with chest radiography +/‐ sputum cytology may leads to lower lung cancer 5‐year survival ‐ More frequent chest x‐ray screening… compared with less intense screening (low certainty).

1 finding from 1 review

Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening

Lung cancer 5‐year survival ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer

Lung cancer screening with chest radiography +/‐ sputum cytology probably leads to lower lung cancer 5‐year survival ‐ Annual chest x‐ray plus 4‐monthly… compared with less intense screening (moderate certainty).

1 finding from 1 review

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Patients' quality of life · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Overall survival · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Delay in start of radiation treatment · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis) · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Tilting-type RDP (minor connector design) vs Functional and sanitary RDP designs

Patient satisfaction · Partially edentulous patients with a distal-extension RDP (minor connector); cross-over
1 finding from 1 review

Altered-cast technique RDP vs One-piece cast RDP

Patients with increased abutment tooth mobility · Partially edentulous patients treated with a distal-extension RDP

Altered-cast technique RDP showed no clear difference in patients with increased abutment tooth mobility compared with one-piece cast RDP; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Transcutaneous electric nerve stimulation (TENS)

Pain in temporomandibular joint (TMJ) · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis clinical,…
1 finding from 1 review

Occlusal splint vs Transcutaneous electric nerve stimulation (TENS)

Clicks in TMJ on oral opening and closing · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis clinical,…

Occlusal splint showed no clear difference in clicks in TMJ on oral opening and closing compared with transcutaneous electric nerve stimulation (TENS); GRADE not reported.

2 findings from 1 review

Occlusal splint vs Transcutaneous electric nerve stimulation (TENS)

Headache · People with sleep bruxism (tooth grinding or clenching); children (greater than 1 year old) and adults; diagnosis clinical,…
1 finding from 1 review
  • Occlusal splint versus TENS, headaches (Alvarez-Arenal 2002): the event did not occur in either group, so the risk ratio was not estimable (Risk Ratio, M-H, Fixed, 95% CI; subtotals only).
    1 study
    GRADE not reported

Summary of findings table ‐ Silicone earplugs vs no earplugs

Cerebral palsy · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes cerebral palsy at 18 to 22 months' corrected age compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

Normal auditory functioning at discharge · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes normal auditory functioning at discharge compared with no earplugs (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Silicone earplugs vs no earplugs

All‐cause mortality during hospital stay · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes all‐cause mortality during hospital stay compared with no earplugs (very low certainty).

1 finding from 1 review