Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Remote ischaemic preconditioning (RIPC) vs no RIPC

Limb loss (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in limb loss (within 1 month after operation) compared with no RIPC (low certainty).

1 finding from 1 review

Endolymphatic sac decompression vs placebo (sham surgery)

Improvement in vertigo (complete resolution) at 6 to ≤ 12 months (12 months) · Ménière’s disease

It is very uncertain whether endolymphatic sac decompression changes improvement in vertigo (complete resolution) at 6 to ≤ 12 months (12… compared with placebo (sham surgery) (very low certainty).

1 finding from 1 review

Locking plate vs locking intramedullary nail

Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

Locking plate showed no clear difference in self‐reported shoulder function: functional scoresb(higher = better… compared with locking intramedullary nail (low certainty).

3 findings from 1 review

Locking plate vs locking intramedullary nail

Adverse events: number of participants with complications · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

It is very uncertain whether locking plate changes adverse events: number of participants with complications compared with locking intramedullary nail (very low certainty).

1 finding from 1 review

Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty

Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)
3 findings from 1 review