Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Illicit opioid use · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in illicit opioid use compared with different full opioid agonists or partial opioid agonists (methadone… (moderate certainty).

3 findings from 1 review

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Retention [ · pharmaceutical opioid dependent people

Full opioid agonists may leads to higher retention compared with different full opioid agonists or partial opioid agonists (methadone… (low certainty).

1 finding from 1 review

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Adverse effects · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in adverse effects compared with different full opioid agonists or partial opioid agonists (methadone… (low certainty).

1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Physiological measures: heart rate and core temperature · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Adverse effects: impaired cognition and blurred vision · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Utilization—at 6 months postabortion · women who experienced abortions and requested a reversible contraceptive method

Immediate may leads to higher utilization—at 6 months postabortion compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Unintended pregnancy · women who experienced abortions and requested a reversible contraceptive method

Immediate probably leads to lower unintended pregnancy—at 6 months postabortion compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Rate of initiation of contraceptive implants—following medical abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate probably leads to higher rate of initiation of contraceptive implants—following medical… compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Rate of initiation of contraceptive implants—following surgical abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate may leads to higher rate of initiation of contraceptive implants—following surgical… compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—overall failure rate at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—overall failure rate at compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—require extra medication for complete abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—require extra medication for… compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—require surgery for complete abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—require surgery for complete… compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Bleeding side effects—at 1 month postabortion · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in bleeding side effects—at 1 month postabortion compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review