Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (horizontal - HDD) compared with no augmentation; GRADE not reported.
1 finding from 1 review
Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Accelerated vs conventional, disease free survival: both trials reported this, but substantial clinical and statistical heterogeneity (P = 0.0004, I2 = 92%) meant a pooled analysis was not reported (Analysis 1.3).
2 studies
GRADE not reported
Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Plaque · Adults with dental implants and peri-implant mucositis at baseline
Triclosan dentifrice showed no clear difference in plaque compared with sodium fluoride dentifrice; GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults with dental implants and healthy peri-implant soft tissues at baseline
Hyaluronic acid gel (brushing) showed no clear difference in change in probing pocket depth compared with chlorhexidine gel (brushing); GRADE not reported.
1 finding from 1 review
Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Rossi et al 1983 (prazepam) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects were…
1 study · 83 participants
GRADE not reported
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Pre-operative radiotherapy (plus surgery) showed no clear difference in locoregional control compared with surgery alone; GRADE not reported.
1 finding from 1 review
RR 0.63 [0.28, 1.46]
1 study
GRADE not reported
Altered fractionation radiotherapy vs Chemoradiotherapy (concurrent, standard fractionation)
Outcome not reported · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
The review found no eligible studies for this question.
1 finding from 1 review
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Polyvariant intramuscular immunoglobulin led to higher improvement in mucositis compared with placebo; GRADE not reported.
1 finding from 1 review
Plaque · Adults with dental implants and healthy peri-implant soft tissues at baseline
Phosphoric etching (acid) gel showed no clear difference in plaque compared with mechanical debridement and polishing; GRADE not reported.
1 finding from 1 review
Augmentation (prosthesis/implant) failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower augmentation (prosthesis/implant) failure compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Poor aesthetics measured by dentist (3 years) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by dentist (3 years) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
After 3 years of loading, the operator judged aesthetics to be poor in 2/7 patients of the Bio-Oss group and in 2/5 of the Bio-Oss plus barrier group; no statistically significant difference.
1 study · 20 participants
GRADE not reported
Daily pain (not improved) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral diclofenac sodium (NSAID) showed no clear difference in daily pain (not improved) compared with placebo; GRADE not reported.
1 finding from 1 review
Soreness in the gums · Adults with dental implants and peri-implant mucositis at baseline
Mechanical debridement plus topical minocycline showed no clear difference in soreness in the gums compared with mechanical debridement plus chlorhexidine gel; GRADE not reported.
1 finding from 1 review
Severe pain for > 1 week · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher severe pain for > 1 week compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Time to complete healing · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients / immunocompromised)
1 finding from 1 review
Two studies. Median time to total healing was shorter for patients receiving oral or intravenous aciclovir than placebo: median of 8 days versus 21 days, P = 0.01 (Shepp 1985); 13.9 days versus 20.7 days, P = 0.08…
2 studies
GRADE not reported
Implant/prosthesis failure and complications · Patients with resorbed maxillae (incl. atrophic sinuses) needing implants
1 finding from 1 review
Costs · Adults (over 18) wearing complete dentures (CD) or removable partial dentures (RPD)
The review found no eligible studies for this question.
1 finding from 1 review
Augmentation procedure (partial) failure · Patients with vertically deficient posterior/anterior mandibular ridges needing implants
Vertical distraction osteogenesis showed no clear difference in augmentation procedure (partial) failure compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.
1 finding from 1 review
Perimplant bone loss · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants
Inlay autogenous bone graft (iliac crest) showed no clear difference in perimplant bone loss compared with inlay bone substitute (Bio-Oss block); GRADE not reported.
1 finding from 1 review