Findings

What do systematic reviews say?

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

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No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Prostacyclin vs control

mPAP (the higher the mPAP, the worse the pulmonary hypertension) · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1132 participants
Low

Prostacyclin vs control

PVR · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 658 participants
Moderate

Prostacyclin vs control

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 868 participants
Low

Prostacyclin vs control

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1060 participants
Moderate

Bispectral index vs treatment guided by clinical assessment alone?

ICU length of stay (general intensive care patients) · Mechanically ventilated adults in the intensive care unit

1 finding from 1 review

BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

SSRIs or SNRIs vs placebo

Headache intensity (mean score) · patients with tension‐type headache

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

SSRIs or SNRIs vs other antidepressants

Headache intensity (mean score) · patients with tension‐type headache

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 152 participants
Very low

Intervention not reported

Angiotensin receptor blocker (high‐ versus medium‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 237 participants
Very low

Intervention not reported

Angiotensin receptor blocker (medium‐ versus low‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 160 participants
Very low

Intervention not reported

Angiotensin‐converting enzyme inhibitor · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Angiotensin receptor blocker (high‐ versus low‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 418 participants
Low

Intervention not reported

ICU length of stay (general intensive care patients) · Adult patients in intensive care

1 finding from 1 review

Pulmonary artery catheters for adult patients in intensive care 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2723 participants
High

Intervention not reported

Hospital length of stay (general intensive care patients) · Adult patients in intensive care

1 finding from 1 review

Pulmonary artery catheters for adult patients in intensive care 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1689 participants
High

Intensive follow‐up vs less intensive follow‐up

Overall survival

Intensive follow‐up showed no clear difference in overall survival compared with less intensive follow‐up (high certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
HR 0.91 [0.8, 1.04]
15 studies · 12528 participants
High

Intensive follow‐up vs less intensive follow‐up

Colorectal cancer‐specific survival

Intensive follow‐up showed no clear difference in colorectal cancer‐specific survival compared with less intensive follow‐up (moderate certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
HR 0.93 [0.81, 1.07]
11 studies · 11771 participants
Moderate

Intensive follow‐up vs less intensive follow‐up

Proportion of participants with relapse‐free survival at ≥ 12 months

Intensive follow‐up showed no clear difference in relapse‐free survival compared with less intensive follow‐up (high certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
HR 1.05 [0.92, 1.21]
16 studies · 8047 participants
High

Intensive follow‐up vs less intensive follow‐up

Salvage surgery (SS)

Intensive follow‐up leads to higher salvage surgery (surgery at relapse with curative intent) compared with less intensive follow‐up (high certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
RR 1.98 [1.53, 2.56]
13 studies · 5157 participants
High

Intensive follow‐up vs less intensive follow‐up

Interval recurrences (IR)

Intensive follow‐up probably leads to lower interval recurrences (recurrence CRC diagnosed between scheduled compared with less intensive follow‐up (moderate certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
RR 0.59 [0.41, 0.86]
7 studies · 3933 participants
Moderate

Intensive follow‐up vs less intensive follow‐up

Harms Colonoscopy complications ‐ bowel perforation

It is very uncertain whether intensive follow‐up changes harms Colonoscopy complications ‐ bowel perforation compared with less intensive follow‐up (very low certainty).

1 finding from 1 review

Follow‐up strategies for patients treated for non‐metastatic colorectal cancer 2019 · Cochrane Headline outcomes only
RR 6.83 [0.36, 131.21]
1 study · 326 participants
Very low

High‐intensity exercise vs low‐intensity exercise programmes four to six weeks after lumbar disc surgery

Pain (short term) VAS · patients four to six weeks after lumbar disc surgery

1 finding from 1 review

Rehabilitation after lumbar disc surgery 2014 · Cochrane Headline outcomes only
no estimate extracted
103 participants
Very low