Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,097 questions · 1,119 findings · 70 reviews · Kidney and Transplant

No studies found 271 · 24.2%GRADE not reported 17 · 1.5%Very low 271 · 24.2%Low 349 · 31.2%Moderate 182 · 16.3%High 29 · 2.6%

D‐mannose (2 g) vs nitrofurantoin (50 mg)

Symptomatic, culture‐verified UTI Women with recurrent UTI · women with acute cystitis or history of recurrent acute cystitis (preventing and treating)

It is very uncertain whether D‐mannose (2 g) changes symptomatic and bacteriuria‐confirmed UTI (positive culture) compared with nitrofurantoin (50 mg) (very low certainty).

1 finding from 1 review

More intensive vs less intensive insulin therapy

Transplant or graft survival · pre‐existing and new‐onset diabetes in kidney transplant recipients

It is very uncertain whether more intensive changes transplant or graft survival compared with less intensive insulin therapy (very low certainty).

1 finding from 1 review