Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

285 questions · 327 findings · 36 reviews · Headline outcomes only

No studies found 129 · 39.4%GRADE not reported 11 · 3.4%Very low 82 · 25.1%Low 64 · 19.6%Moderate 38 · 11.6%High 3 · 0.9%

IStent in combination with phacoemulsification vs phacoemulsification alone

Proportion of participants who were drop‐free · open‐angle glaucoma

It is very uncertain whether IStent in combination with phacoemulsification changes proportion of participants who were drop‐free compared with phacoemulsification alone (very low certainty).

1 finding from 1 review

Laparoscopic vs open appendectomy

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with suspected appendicitis
3 findings from 1 review

Laparoscopic vs open appendectomy

Length of hospital stay · patients with suspected appendicitis
4 findings from 1 review
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Laparoscopic vs open appendectomy

Wound infection · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic probably leads to lower wound infections compared with open appendectomy (moderate certainty).

3 findings from 1 review

Laparoscopic vs open appendectomy

Intra‐abdominal abscess · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic showed no clear difference in intra‐abdominal abscesses compared with open appendectomy (low certainty).

4 findings from 1 review
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