Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

LongoVital (herbal component alone) vs placebo

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Daily chewing gum for 2 weeks or longer vs No gum chewing or control

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

codex

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Catheter‐related blood stream infection · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in catheter‐related blood stream infection (CRBSI) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

All‐cause mortality · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in all‐cause mortality compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Pain № of participants: 193 (2 RCTs) · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in pain № of participants: 193 (2 RCTs) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

LongoVital (herbal plus vitamin component) vs placebo

Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • Forty patients were randomised to receive LongoVital (herbal plus vitamin) or placebo (Kolseth 2005). Data presented as medians with 95% confidence intervals, unsuitable for further analysis. The authors report no…
    1 study · 40 participants
    GRADE not reported