Findings

What do systematic reviews say?

230 questions · 235 findings · 17 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 71 · 30.2%GRADE not reported 17 · 7.2%Very low 70 · 29.8%Low 49 · 20.9%Moderate 20 · 8.5%High 8 · 3.4%

2% mepivacaine, 1:20,000 levonordefrin vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (clinical; orphan data) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
No data available for meta-analysis; orphan clinical success data summarized in Table 6 (e.g. clinical anaesthesia success 2% lidocaine 1:100,000 64/110 vs 2% mepivacaine 1:20,000 levonordefrin 99/113). Not…
Studies not reported
GRADE not reported

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% articaine, 1:100,000 epinephrine may leads to higher duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
MD 56.88 [44.08, 69.69]
2 studies · 422 participants
Low

2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

Intervention not reported

Adverse effects Events · Adult participants receiving propofol for induction of anaesthesia

1 finding from 1 review

Lidocaine for reducing propofol‐induced pain on induction of anaesthesia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
32 studies · 4007 participants
Low

Intervention not reported

At least 50% reduction in pain or equivalent · adults with peripheral neuropathic pain conditions

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Intervention not reported

"Moderate" benefit At least 30% reduction in pain · adults with peripheral neuropathic pain conditions

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Intervention not reported

Patient Global Impression of Change much or very much improved · adults with peripheral neuropathic pain conditions

The review found no eligible studies for this question.

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse event withdrawals · adults with peripheral neuropathic pain conditions

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 263 participants
Very low

Intervention not reported

Serious adverse events · adults with peripheral neuropathic pain conditions

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 263 participants
Very low

Intervention not reported

Death · adults with peripheral neuropathic pain conditions

1 finding from 1 review

Topical lidocaine for neuropathic pain in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 210 participants
GRADE not reported