Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

343 questions · 347 findings · 29 reviews · Eyes and Vision

No studies found 94 · 27.1%GRADE not reported 11 · 3.2%Very low 81 · 23.3%Low 110 · 31.7%Moderate 47 · 13.5%High 4 · 1.2%

Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy

Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma

Microcatheter‐assisted trabeculotomy probably leads to higher proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (moderate certainty).

1 finding from 1 review

Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy

Hyphema · children at or before five years of age with primary congenital glaucoma

Microcatheter‐assisted trabeculotomy probably leads to higher adverse outcomes— hyphema Up to 1 year after surgery compared with conventional trabeculotomy (moderate certainty).

1 finding from 1 review

Intervention not reported

Fear of falling scores at 6 months Assessed by Short Falls Efficacy Scale‐International · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in fear of falling scores at 6 months Assessed by Short Falls Efficacy… (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life at 6 months Assessed by 12‐Item Short Form Health Survey · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in quality of life at 6 months Assessed by 12‐Item Short Form Health… (low certainty).

1 finding from 1 review

Intervention not reported

Physical activity at 6 months Assessed by self‐reported physical activity · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in physical activity at 6 months Assessed by self‐reported physical… (low certainty).

1 finding from 1 review

Intervention not reported

Fear of falling scores at 6 months Assessed by Short Falls Efficacy Scale‐International · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in fear of falling scores at 6 months Assessed by Short Falls Efficacy… (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life at 6 months Assessed by European Quality of Life‐15 · older adults (aged 60 and over) with irreversible visual impairment

The intervention showed no clear difference in quality of life at 6 months Assessed by European Quality of Life‐15 (low certainty).

1 finding from 1 review

Therapeutic contact lens vs topical lubrication

Resolution of symptoms · people with recurrent corneal erosion syndrome without previous surgical intervention

Therapeutic contact lens showed no clear difference in resolution of symptoms after treatment compared with topical lubrication (low certainty).

1 finding from 1 review

Phototherapeutic keratectomy vs alcohol delamination

Recurrences requiring further treatment · people with recurrent corneal erosion syndrome without previous surgical intervention

It is very uncertain whether phototherapeutic keratectomy changes recurrences requiring further treatment compared with alcohol delamination (very low certainty).

1 finding from 1 review

Diamond burr superficial keratectomy (after epithelial debridement) vs sham diamond burr (after epithelial debridement)

Recurrence after complete or partial resolution · people with recurrent corneal erosion syndrome without other corneal basement membrane dystrophy

Diamond burr superficial keratectomy (after epithelial debridement) probably leads to lower recurrence after complete or partial resolution compared with sham diamond burr (after epithelial debridement) (moderate certainty).

1 finding from 1 review