Medication given before LTP showed no clear difference in IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with the same medication given after LTP (moderate certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.82 [0.25, 2.63]
4 studies · 319 participants
Moderate

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication given before LTP changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with the same medication given after LTP (very low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 1.55 [0.19, 12.43]
4 studies · 319 participants
Very low

Medication given before LTP vs the same medication given after LTP

Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 198 participants
Moderate

Medication given before LTP vs the same medication given after LTP

Adverse events during treatment period · people with glaucoma receiving LTP

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medication vs placebo

Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 151 participants
Moderate

Medication vs placebo

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication may leads to lower IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with placebo (low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.17 [0.09, 0.31]
5 studies · 634 participants
Low

Medication vs placebo

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with placebo (very low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.22 [0.11, 0.42]
9 studies · 817 participants
Very low

Medication vs placebo

Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 151 participants
Moderate

Medication vs placebo

Adverse events ‐ conjunctival blanching during study period · people with glaucoma receiving LTP

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 319 participants
Moderate

Brimonidine vs apraclonidine

IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP

It is very uncertain whether brimonidine changes IOP increase of ≥ 5 mmHg within 2 hours compared with apraclonidine (very low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 2.28 [0.32, 16.03]
2 studies · 71 participants
Very low

Brimonidine vs apraclonidine

IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 179 participants
Very low

Intervention not reported

Serious adverse events · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2312 participants
Low

Intervention not reported

Cardiovascular mortality · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2281 participants
Very low

Intervention not reported

(1) Non‐fatal myocardial infarction (2) Non‐fatal stroke (3) Congestive heart failure · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2279 participants
Very low