Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

267 questions · 280 findings · 47 reviews

No studies found 80 · 28.6%GRADE not reported 11 · 3.9%Very low 96 · 34.3%Low 50 · 17.9%Moderate 40 · 14.3%High 3 · 1.1%

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication given before LTP showed no clear difference in IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with the same medication given after LTP (moderate certainty).

1 finding from 1 review

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication given before LTP changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with the same medication given after LTP (very low certainty).

1 finding from 1 review